Only two nuclear encoded inteins have been described. The first, SceVMA, was found in a
vacuolar ATPase gene of Saccharomyces cerevisiae and related yeasts. The second …

Background We recently described a mini-intein in the PRP8 gene of a strain of the
basidiomycete Cryptococcus neoformans, an important fungal pathogen of humans. This …

Inteins or" internal proteins" are coding sequences that are transcribed and translated with
flanking sequences (exteins). After translation, the inteins are excised by an autocatalytic …

We have used comparative sequence analysis to identify an intein‐like sequence (protein
splicing element) present in Cryptococcus neoformans, a fungal pathogen of humans. The …

Until recently the only intein known to be encoded by the nuclear genome of a eukaryote
was the VMA intein in the vacuolar ATPase precursor of several species of saccharomycete …

Inteins are intervening sequences that are transcribed and translated with flanking host
protein sequences and then self-excised by protein splicing. Bi-functional inteins also …

Inteins are self-splicing intervening sequences in proteins, and inteins of pathogenic
organisms can be attractive drug targets. Here, we report an intein in important fungal …

In Cryptococcus neoformans, nearly all genes are interrupted by small introns. In recent
years, genome annotation and genetic analysis have illuminated the major roles these …

An intein is a protein sequence embedded within a precursor protein that is excised during
protein maturation. Inteins were first found encoded in the VMA gene of Saccharomyces …

The PRP8 intein is the most widespread intein among the Kingdom Fungi. This genetic
element occurs within the prp8 gene, and is transcribed and translated simultaneously with …