The Multiple Sclerosis Outcome Assessments Consortium (MSOAC) includes
representatives from advocacy organizations, Food and Drug Administration (FDA) …

Disability measures in multiple sclerosis (MS) rely heavily on ambulatory function, and
current metrics fail to capture potentially important variability in walking behavior. We sought …

Walking impairment is a debilitating symptom of Multiple Sclerosis (MS), a disease affecting
2.8 million people worldwide. While clinicians' in-person observational gait assessments are …

Goal: Smartphone and wearable devices may act as powerful tools to remotely monitor
physical function in people with neurodegenerative and autoimmune diseases from out-of …

Background The available clinical outcome measures of disability in multiple sclerosis are
not adequately responsive or sensitive. Objective To investigate the feasibility of inertial …

Gait speed is a powerful clinical marker for mobility impairment in patients suffering from
neurological disorders. However, assessment of gait speed in coordination with delivery of …

Accelerometers are seemingly a criterion standard of real-life walking mobility and this is
supported by assumptions and empirical data. This application would be strengthened by …

Background Limited walking ability is an important problem for patients with multiple
sclerosis. A better understanding of how gait impairments lead to limited walking ability may …

Background Wearable sensor technologies have the potential to improve monitoring in
people with multiple sclerosis (MS) and inform timely disease management decisions …

Gait and balance deficits are a frequent complaint in MS but poorly captured by stopwatch-
timed tests or rating scales. Body-worn accelerometers and gyroscopes are able to detect …