Conformational study of a custom antibacterial peptide cecropin B1: implications of the lytic activity

S Srisailam, AI Arunkumar, W Wang, C Yu… - Biochimica et Biophysica …, 2000 - Elsevier
Cecropin B1 (CB1) with two amphipathic α-helical segments is a derivative of the natural
antibacterial peptide, cecropin B. The assays of cell lysis show that, compared with cecropin …

Design, synthesis and antibacterial activity of cecropin‐like model peptides

J FINK, A BOMAN, HG BOMAN… - International Journal of …, 1989 - Wiley Online Library
In order to investigate structure‐activity relationships of cecropins, model peptides that mimic
certain structural features of the cecropin molecules were designed and synthesized. The …

Microscopic observations of the different morphological changes caused by anti‐bacterial peptides on Klebsiella pneumoniae and HL‐60 leukemia cells

SC Chan, WL Yau, W Wang, DK Smith… - Journal of peptide …, 1998 - Wiley Online Library
Natural anti-bacterial peptides cecropin B (CB) and its analogs cecropin B-1 (CB-1),
cecropin B-2 (CB-2) and cecropin B-3 (CB-3) were prepared. The different characteristics of …

The solution conformation of the antibacterial peptide cecropin A: a nuclear magnetic resonance and dynamical simulated annealing study

TA Holak, A Engstroem, PJ Kraulis, G Lindeberg… - Biochemistry, 1988 - ACS Publications
Tadeusz A. Holak,* Ake Engstrom, § Per J. Kraulis, 11 Gunnar Lindeberg, § HansBennich, §
T. Alwyn Jones, 11 Angela M. Gronenborn,*'*'-1 and G. Marius Clore*'*'1 Max-Planck-Institut …

N-terminal analogs of cecropin A: synthesis, antibacterial activity, and conformational properties

D Andreu, RB Merrifield, H Steiner, HG Boman - Biochemistry, 1985 - ACS Publications
Six analogues of the 37-residue antibacterial peptide cecropin A were synthesized by the
solid-phase method: cecropin A-(2-37),[Glu2] cecropin A,[Pro4] cecropin A,[Glu6] cecropin …

The structure of the mammalian antibacterial peptide cecropin P1 in solution, determined by proton‐NMR

D Sipos, M Andersson… - European Journal of …, 1992 - Wiley Online Library
Cecropins are peptides with antibacterial activity originally found in insects. Recently a
cecropin‐type peptide was isolated from pig intestine. This peptide, porcine cecropin P1 …

Crumpled structure of the custom hydrophobic lytic peptide cecropin B3

S Srisailam, TKS Kumar, AI Arunkumar… - European journal of …, 2001 - Wiley Online Library
The solution structure of a custom lytic peptide, cecropin B3 (CB3), having two identical
hydrophobic segments on both the N‐and C‐termini, was investigated by two‐dimensional …

Mode of action of the antibacterial cecropin B2: a spectrofluorometric study

E Gazit, WJ Lee, PT Brey, Y Shai - Biochemistry, 1994 - ACS Publications
Revised Manuscript Received July 7, 1994® abstract: Cecropin B2 (CecB) is a 35 amino
acid residue, antibacterial peptide that was isolated from the hemolymph and cuticular …

All-D-cecropin B: synthesis, conformation, lipopolysaccharide binding, and antibacterial activity

JM Bland, AJ De Lucca, TJ Jacks, CB Vigo - Molecular and cellular …, 2001 - Springer
Cecropin B (LCB) is a natural peptide with antibacterial and antifungal properties. The
enantiomer of LCB, containing all-D amino acids (DCB), was synthesized to examine its …

Design and analysis of structure–activity relationship of novel antimicrobial peptides derived from the conserved sequence of cecropin

G Hao, YH Shi, JH Han, QH Li… - Journal of Peptide …, 2008 - Wiley Online Library
We have de novo designed four antimicrobial peptides AMP‐A/B/C/D, the 51‐residues
peptides, which are based on the conserved sequence of cecropin. In the present study, the …