In the search for new therapeutic agents for Chagas' disease, we screened extracts obtained
from the Brazilian plant Pterodon pubescens found commercially in the medicinal flora …

The trypanocidal activity of crude hydro alcoholic extracts and several fractions of 13 plants
from Brazilian Atlantic Rain Forest were tested in vitro against epimastigote and …

Twenty-seven diterpenes, including abietanes, labdanes, abeoabietanes, halimanes, and
pimaranes, have been evaluated against epimastigote and intracellular amastigote forms of …

Chagas' disease is a debilitating but comparatively neglected illness that affects about 15
million people. There is an urgent need to develop new, more effective, and less-toxic …

Bioactivity of fractions and compounds obtained from Polygala sabulosa against
Trypanosoma cruzi epimastigote, blood trypomastigote and amastigote forms were …

BACKGROUND Recent studies showed that essential oils from different pepper species
(Piper spp.) have promising leishmanicidal and trypanocidal activities. OBJECTIVES In …

Essential/volatile oils (EOs) from plants used in the traditional medicine are known as a rich
source of chemically diverse compounds with relevant biological activities. In this work we …

Chagas disease is a neglected tropical disease that is caused by the protozoan
Trypanosoma cruzi and represents a serious health problem, especially in Latin America …

Two hundred fifteen compounds isolated from plants of Northeastern Brazil flora have been
assayed against epimastigote forms of Trypanosoma cruzi, using the tetrazolium salt MTT as …

In order to determine the in vivo activity against the protozoan Trypanosoma cruzi, two doses
(50 and 75 mg/kg) of a chloroform extract of Carica papaya seeds were evaluated compared …