Background Effective malaria control has successfully reduced the malaria burden in many
countries, but to eliminate malaria, these countries will need to further improve their control …

Artemesinin-combination therapies (ACT) for falciparum malaria reduce gametocyte
carriage, and therefore reduce transmission. Artemisinin derivatives will act against only …

Background. Artemisinin-based combination therapy is very effective in clearing asexual
stages of malaria and reduces gametocytemia, but may not affect mature gametocytes …

Background Primaquine (PQ) is the only currently licensed antimalarial that prevents
Plasmodium vivax (Pv) relapses. It also clears mature P. falciparum (Pf) gametocytes …

Following the recent successes of malaria control in sub-Saharan Africa, the
gametocytocidal drug primaquine needs evaluation as a tool to further reduce the …

Summary Between January 2000 and December 2002 monthly rainfall was correlated with
the proportion of patients with hyperparasitaemic Plasmodium falciparum malaria and with …

Background Single low dose primaquine (SLD PQ, 0.25 mg/kg) is recommended in
combination with artemisinin-based combination therapy (ACT) as a gametocytocide to …

Abstract Background Since the World Health Organization recommended single low-dose
(0.25 mg/kg) primaquine (PQ) in combination with artemisinin-based combination therapies …

Individual-based models provide powerful tools to model complex interactions characterized
by individual variability. This paper presents an object-oriented design for individual-based …

Background Primaquine is an important gametocytocidal drug that is combined with
conventional malaria treatment for prevention of Plasmodium falciparum malaria …