Background The purpose of this study was to evaluate the effects of cytoreductive
nephrectomy (CN) and metastasectomies on the survival of patients with synchronous …

Background The benefit of cytoreductive nephrectomy (CN) for overall survival (OS) is
unclear in patients with synchronous metastatic renal cell carcinoma (mRCC) in the era of …

Background and objective: Most of the studies on metastasectomy in renal cell cancer are
based on metachronous, often oligometastatic disease. Prior data on the impact of …

BACKGROUND: The survival impact of metastasectomy for metastatic renal cell carcinoma
(mRCC) is still an active research field, particularly in the multimodal/targeted therapy era …

Purpose With the emergence of targeted therapies, the indications of cytoreductive
nephrectomy have to be redefined. This review article presents the evidence data guiding …

Purpose To evaluate the prognostic role of cytoreductive nephrectomy (CN) in patients with
synchronous metastatic renal-cell carcinoma (mRCC). Patients and Methods We analyzed …

Introduction Metastasectomy (MSX) is considered a treatment option in patients with
metastatic renal cell carcinoma (mRCC) at diagnosis, but its role in the targeted therapy era …

Objectives The role of cytoreductive nephrectomy (CN) in the treatment of patients harboring
metastatic renal cell carcinoma (mRCC) has become controversial since the emergence of …

Purpose Metastatic renal cell carcinoma (mRCC) represents a significant and rising burden
of disease, with rapidly evolving treatment modalities. The role of cytoreductive nephrectomy …

Purpose To test the hypothesis that cytoreductive nephrectomy (CN) improves overall
survival (OS) of patients with synchronous metastatic renal cell carcinoma (mRCC), who …