Temporal analysis of active and passive transport in living cells

D Arcizet, B Meier, E Sackmann, JO Rädler… - Physical review letters, 2008 - APS
The cellular cytoskeleton is a fascinating active network, in which Brownian motion is
intercepted by distinct phases of active transport. We present a time-resolved statistical …

Diffusion and directed motion in cellular transport

A Caspi, R Granek, M Elbaum - Physical Review E, 2002 - APS
We study the motion of a probe driven by microtubule-associated motors within a living
eukaryotic cell. The measured mean square displacement,< x (t) 2> of engulfed 2 and 3 μ m …

On the spontaneous collective motion of active matter

S Wang, PG Wolynes - … of the National Academy of Sciences, 2011 - National Acad Sciences
Spontaneous directed motion, a hallmark of cell biology, is unusual in classical statistical
physics. Here we study, using both numerical and analytical methods, organized motion in …

Enhanced diffusion in active intracellular transport

A Caspi, R Granek, M Elbaum - Physical review letters, 2000 - APS
We show that within a living eukaryotic cell, mean square displacement of an engulfed
microsphere shows enhanced diffusion scaling as t 3/2 at short times, with a clear crossover …

Modeling cytoskeletal traffic: an interplay between passive diffusion and active transport

I Neri, N Kern, A Parmeggiani - Physical review letters, 2013 - APS
We introduce the totally asymmetric simple exclusion process with Langmuir kinetics on a
network as a microscopic model for active motor protein transport on the cytoskeleton …

Cytoplasmic diffusion: molecular motors mix it up

CP Brangwynne, GH Koenderink… - The Journal of cell …, 2008 - rupress.org
Random motion within the cytoplasm gives rise to molecular diffusion; this motion is
essential to many biological processes. However, in addition to thermal Brownian motion …

Intracellular transport by active diffusion

CP Brangwynne, GH Koenderink, FC MacKintosh… - Trends in cell …, 2009 - cell.com
All substances exhibit constant random motion at the microscopic scale. This is a direct
consequence of thermal agitation, and leads to diffusion of molecules and small particles in …

[HTML][HTML] Enhanced reaction kinetics in biological cells

C Loverdo, O Bénichou, M Moreau, R Voituriez - Nature physics, 2008 - nature.com
The cell cytoskeleton is a striking example of an 'active'medium driven out-of-equilibrium by
ATP hydrolysis. Such activity has been shown to have a spectacular impact on the …

Deterministic patterns in cell motility

I Lavi, M Piel, AM Lennon-Duménil, R Voituriez… - Nature Physics, 2016 - nature.com
Cell migration paths are generally described as random walks, associated with both intrinsic
and extrinsic noise. However, complex cell locomotion is not merely related to such …

Random walks of cytoskeletal motors in open and closed compartments

R Lipowsky, S Klumpp, TM Nieuwenhuizen - Physical Review Letters, 2001 - APS
Random walks of molecular motors, which bind to and unbind from cytoskeletal filaments,
are studied theoretically. The bound and unbound motors undergo directed and nondirected …