Background: The interaction among inflammation, Hemostasis, and fibrinolysis plays a
major role in the genesis of coronary artery disease (CAD). The aim of the study was to …

This study aimed to compare the effects of clopidogrel, acetylsalicylic acid (ASA), and the
combination of both substances on platelet aggregation and expression of platelet …

OBJECTIVES We sought to compare the inhibitory effects of the combination of two doses of
aspirin plus clopidogrel with either drug alone on platelet aggregation and activation …

Background Impaired response to dual antiplatelet therapy is associated with worse
cardiovascular outcome. Besides antiplatelet effects, there is evidence that both clopidogrel …

Background Recently we have demonstrated a dose-dependent improvement of endothelial
function after administration of a single loading dose of clopidogrel in patients with coronary …

Ten patients with chronic stable angina pectoris and ten aged-matched healthy controls
were investigated. Aspirin was given as 160 mg/day and clopidogrel as 300 mg loading …

Formation of platelet‐leukocyte aggregates via the CD62 ligand represents an important
mechanism by which leukocytes contribute to thrombotic events. In a cross‐sectional study …

Aspirin reduces several pro-inflammatory markers in patients with coronary heart disease
(CHD), while limited data exists with clopidogrel. The aim of the present substudy of ASCET …

Atherosclerosis is an inflammatory response of the arterial wall to 'injury', which is
prominently driven by inflammatory factors. Clopidogrel reduces early atherosclerosis …

The anti-platelet drug clopidogrel has been shown to modulate adhesion molecule and
cytokine expression, both playing an important role in the pathogenesis of atherosclerosis …