[HTML][HTML] Heterogeneities shape passive intracellular transport
A living cell's interior is one of the most complex and intrinsically dynamic systems, providing
an elaborate interplay between cytosolic crowding and ATP-driven motion that controls …
an elaborate interplay between cytosolic crowding and ATP-driven motion that controls …
[HTML][HTML] Local motion analysis reveals impact of the dynamic cytoskeleton on intracellular subdiffusion
Intracellular transport is a complex interplay of ballistic transport along filaments and of
diffusive motion, reliably delivering material and allowing for cell differentiation, migration …
diffusive motion, reliably delivering material and allowing for cell differentiation, migration …
Anomalous intracellular transport phases depend on cytoskeletal network features
B Maelfeyt, SMA Tabei, A Gopinathan - Physical Review E, 2019 - APS
Intracellular transport in eukaryotic cells consists of phases of passive, diffusion-based
transport and active, motor-driven transport along filaments that make up the cell's …
transport and active, motor-driven transport along filaments that make up the cell's …
Emergent spatiotemporal organization in stochastic intracellular transport dynamics
The interior of a living cell is an active, fluctuating, and crowded environment, yet it maintains
a high level of coherent organization. This dichotomy is readily apparent in the intracellular …
a high level of coherent organization. This dichotomy is readily apparent in the intracellular …
Modeling cytoskeletal traffic: an interplay between passive diffusion and active transport
I Neri, N Kern, A Parmeggiani - Physical review letters, 2013 - APS
We introduce the totally asymmetric simple exclusion process with Langmuir kinetics on a
network as a microscopic model for active motor protein transport on the cytoskeleton …
network as a microscopic model for active motor protein transport on the cytoskeleton …
Enhanced diffusion in active intracellular transport
We show that within a living eukaryotic cell, mean square displacement of an engulfed
microsphere shows enhanced diffusion scaling as t 3/2 at short times, with a clear crossover …
microsphere shows enhanced diffusion scaling as t 3/2 at short times, with a clear crossover …
[HTML][HTML] Anomalous diffusion of single particles in cytoplasm
The crowded intracellular environment poses a formidable challenge to experimental and
theoretical analyses of intracellular transport mechanisms. Our measurements of single …
theoretical analyses of intracellular transport mechanisms. Our measurements of single …
[HTML][HTML] Cytoplasmic RNA-protein particles exhibit non-Gaussian subdiffusive behavior
The cellular cytoplasm is a complex, heterogeneous environment (both spatially and
temporally) that exhibits viscoelastic behavior. To further develop our quantitative insight into …
temporally) that exhibits viscoelastic behavior. To further develop our quantitative insight into …
Elucidating the origin of heterogeneous anomalous diffusion in the cytoplasm of mammalian cells
Diffusion of tracer particles in the cytoplasm of mammalian cells is often anomalous with a
marked heterogeneity even within individual particle trajectories. Despite considerable …
marked heterogeneity even within individual particle trajectories. Despite considerable …
[HTML][HTML] Diffusion in cytoplasm: effects of excluded volume due to internal membranes and cytoskeletal structures
IL Novak, P Kraikivski, BM Slepchenko - Biophysical journal, 2009 - cell.com
The intricate geometry of cytoskeletal networks and internal membranes causes the space
available for diffusion in cytoplasm to be convoluted, thereby affecting macromolecule …
available for diffusion in cytoplasm to be convoluted, thereby affecting macromolecule …