[HTML][HTML] Heterogeneities shape passive intracellular transport

P Witzel, M Götz, Y Lanoiselée, T Franosch… - Biophysical journal, 2019 - cell.com
A living cell's interior is one of the most complex and intrinsically dynamic systems, providing
an elaborate interplay between cytosolic crowding and ATP-driven motion that controls …

[HTML][HTML] Local motion analysis reveals impact of the dynamic cytoskeleton on intracellular subdiffusion

M Otten, A Nandi, D Arcizet, M Gorelashvili, B Lindner… - Biophysical journal, 2012 - cell.com
Intracellular transport is a complex interplay of ballistic transport along filaments and of
diffusive motion, reliably delivering material and allowing for cell differentiation, migration …

Anomalous intracellular transport phases depend on cytoskeletal network features

B Maelfeyt, SMA Tabei, A Gopinathan - Physical Review E, 2019 - APS
Intracellular transport in eukaryotic cells consists of phases of passive, diffusion-based
transport and active, motor-driven transport along filaments that make up the cell's …

Emergent spatiotemporal organization in stochastic intracellular transport dynamics

K Joshi, HM York, CS Wright, RR Biswas… - Annual Review of …, 2024 - annualreviews.org
The interior of a living cell is an active, fluctuating, and crowded environment, yet it maintains
a high level of coherent organization. This dichotomy is readily apparent in the intracellular …

Modeling cytoskeletal traffic: an interplay between passive diffusion and active transport

I Neri, N Kern, A Parmeggiani - Physical review letters, 2013 - APS
We introduce the totally asymmetric simple exclusion process with Langmuir kinetics on a
network as a microscopic model for active motor protein transport on the cytoskeleton …

Enhanced diffusion in active intracellular transport

A Caspi, R Granek, M Elbaum - Physical review letters, 2000 - APS
We show that within a living eukaryotic cell, mean square displacement of an engulfed
microsphere shows enhanced diffusion scaling as t 3/2 at short times, with a clear crossover …

[HTML][HTML] Anomalous diffusion of single particles in cytoplasm

BM Regner, D Vučinić, C Domnisoru, TM Bartol… - Biophysical journal, 2013 - cell.com
The crowded intracellular environment poses a formidable challenge to experimental and
theoretical analyses of intracellular transport mechanisms. Our measurements of single …

[HTML][HTML] Cytoplasmic RNA-protein particles exhibit non-Gaussian subdiffusive behavior

TJ Lampo, S Stylianidou, MP Backlund, PA Wiggins… - Biophysical journal, 2017 - cell.com
The cellular cytoplasm is a complex, heterogeneous environment (both spatially and
temporally) that exhibits viscoelastic behavior. To further develop our quantitative insight into …

Elucidating the origin of heterogeneous anomalous diffusion in the cytoplasm of mammalian cells

A Sabri, X Xu, D Krapf, M Weiss - Physical Review Letters, 2020 - APS
Diffusion of tracer particles in the cytoplasm of mammalian cells is often anomalous with a
marked heterogeneity even within individual particle trajectories. Despite considerable …

[HTML][HTML] Diffusion in cytoplasm: effects of excluded volume due to internal membranes and cytoskeletal structures

IL Novak, P Kraikivski, BM Slepchenko - Biophysical journal, 2009 - cell.com
The intricate geometry of cytoskeletal networks and internal membranes causes the space
available for diffusion in cytoplasm to be convoluted, thereby affecting macromolecule …