Abstract Three (z)-3-(bromomethylene) thiochroman-4-ones were designed and
synthesized. Their structures were confirmed by MS and 1H NMR. In vitro antifungal …

Abstract Four new 3-substituedmethylenethiochroman-4-one derivatives were prepared
from (z)-3-(chloromethylene) thiochroman-4-one. They were characterized by analytical and …

Abstract Thiochromanones and 1, 3, 4-thiadazoles as heterocyclic compounds have broad
biological activities. In order to find novel compounds with antifungal activity, we synthesized …

A series of novel selenochroman-4-one derivatives bearing semicarbazone or nitrogen
heterocycle was designed, synthesized, tested antifungal activity and characterized via 1 H …

Cancer is a global issue and represents a major public health concern, and it is one of the
main reasons to result the human death.[1] At present, there are four main tumor therapy …

Abstract A series of 3-benzylidenechroman-4-ones, 3-benzylidenethiochroman-4-ones and
2-benzylidene-1-tetralones have been synthesised and tested for their in vitro antifungal …

A series of novel thiochroman‐4‐one derivatives incorporating carboxamide and 1, 3, 4‐
thiadiazole thioether moieties were synthesized. Bioassay results indicated that the EC50 …

A series of 3-substituted-thiochroman-4-one semicarbazone derivatives were designed
based on the bioisosterism and combination principle in drug design. The target compounds …

Abstract A series of novel 2, 3-dihydro-4H-1-benzoselenin-4-one (thio) semicarbazone
derivatives were designed and synthesized by using molecular hybridization approach. All …

A series of 3-substituted thiochromanones has been prepared. Their structures were
confirmed by H¹-NMR and HRMS. All of the synthesized compounds were screened for …