(R)-3,N-Dimethyl-N-[1-methyl-3-(4-methylpiperidin-1-yl)propyl]benzenesulfonamide:  The First Selective 5-HT7 Receptor Antagonist

IT Forbes, S Dabbs, DM Duckworth… - Journal of medicinal …, 1998 - ACS Publications
5-HT1A< 5.1 5-HT2C< 4.8 5-HT1B< 5.3 5-HT4< 5.0 5-HT1D 5.5 5-HT6< 4.8 5-HT1E< 4.8 5-
HT7 7.5 (0.04 (n) 6) 5-HT1F< 5.2 adrenergic R1B< 4.8 5-HT2A< 4.8 dopaminergic D2 5.4 5 …

Alkaloids of Haloxylon salicornicum (Moq.) Bunge ex Boiss.(Chenopodiaceae)

AM El-Shazly, G Dora, M Wink - Die Pharmazie-An …, 2005 - ingentaconnect.com
Haloxylon salicornicum is a desert plant that contains several alkaloids. From the aerial
parts a new piperidyl alkaloid, haloxynine, was isolated and characterized on the basis of …

SB-216641 and BRL-15572–compounds to pharmacologically discriminate h5-HT1B and h5-HT1D receptors

GW Price, MJ Burton, LJ Collin, M Duckworth… - Naunyn-Schmiedeberg's …, 1997 - Springer
Despite only modest homology between h5-HT 1B and h5-HT 1D receptor amino acid
sequences, these receptors display a remarkably similar pharmacology. To date there are …

Synthesis and Pharmacological Characterization of a Series of Geometrically Constrained 5-HT2A/2C Receptor Ligands

JJ Chambers, JC Parrish, NH Jensen… - Journal of medicinal …, 2003 - ACS Publications
In studies of the SAR of phenethylamine-type serotonin 5-HT2A receptor agonists,
substituted conformationally constrained tetrahydronaphthofurans were designed to …

[引用][C] A review on tabernaemontana spp.: Multipotential medicinal plant

A Athipornchai - Asian J. Pharm. Clin. Res, 2018

Pharmacological characterisation of a cloned dog 5-HT1B receptor cell line

MS Beer, MA Heald, G McAllister, JA Stanton - European journal of …, 1998 - Elsevier
In this study, the binding of [3H] 5-HT to the cloned dog 5-hydroxytryptamine1B (dog 5-
HT1B) receptor, stably expressed in Chinese hamster ovary cells (ATCC CCL 61)(CHO-K1) …

N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl) urea: a novel, high-affinity 5-HT2B receptor antagonist

IT Forbes, GE Jones, OE Murphy… - Journal of medicinal …, 1995 - ACS Publications
The 5-HT2 family of receptors is comprised of three sub-types, namely 5-HT2a, 5-HT2B, and
5-HT2c-These receptors have been grouped in the same class on the basis of molecular …

Synthesis and Pharmacological Characterization of Novel 6-Fluorochroman Derivatives as Potential 5-HT1A Receptor Antagonists

T Yasunaga, T Kimura, R Naito, T Kontani… - Journal of medicinal …, 1998 - ACS Publications
A series of novel 6-fluorochroman derivatives was prepared and evaluated as antagonists
for the 5-HT1A receptor. N-2-[[(6-Fluorochroman-8-yl) oxy] ethyl]-4-(4-methoxyphenyl) …

N1-arylsulfonyl-3-(1, 2, 3, 6-tetrahydropyridin-4-yl)-1H-indole derivatives are potent and selective 5-HT6 receptor antagonists

DC Cole, JW Ellingboe, WJ Lennox… - Bioorganic & medicinal …, 2005 - Elsevier
A series of N1-arylsulfonyl-3-(1, 2, 3, 6-tetrahydropyridin-4-yl) indole derivatives was
designed and synthesized. These compounds were shown to have high affinity for the 5 …

1, 2, 4-Benzothiadiazine derivatives as α1 and 5-HT1A receptor ligands

A Tait, A Luppi, S Franchini, E Preziosi… - Bioorganic & medicinal …, 2005 - Elsevier
A series of new 1, 2, 4-benzothiadiazine derivatives with an arylpiperazine mojety linked at
position 3 of the heterocyclic ring were synthesized and assessed for their pharmacological …