Review on MALDI mass spectrometry and its application in clinical research

O Ogundairo, O Ayo-Farai, CP Maduka… - International Medical …, 2023 - fepbl.com
Mass spectrometry has emerged as a powerful analytical tool in various scientific
disciplines, and Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI …

Matrix-assisted laser desorption ionisation (MALDI) mass spectrometry (MS): basics and clinical applications

MZ Israr, D Bernieh, A Salzano… - Clinical Chemistry and …, 2020 - degruyter.com
Background Matrix-assisted laser desorption ionisation (MALDI) mass spectrometry (MS)
has been used for more than 30 years. Compared with other analytical techniques, it offers …

Biomedical application of MALDI mass spectrometry for small‐molecule analysis

JJA van Kampen, PC Burgers… - Mass spectrometry …, 2011 - Wiley Online Library
Matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry (MS) is an emerging
analytical tool for the analysis of molecules with molar masses below 1,000 Da; that is, small …

Recent methodological advances in MALDI mass spectrometry

K Dreisewerd - Analytical and bioanalytical chemistry, 2014 - Springer
Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is widely used
for characterization of large, thermally labile biomolecules. Advantages of this analytical …

Matrix-assisted laser desorption/ionization imaging mass spectrometry

N Zaima, T Hayasaka, N Goto-Inoue… - International journal of …, 2010 - mdpi.com
Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is a powerful tool
that enables the simultaneous detection and identification of biomolecules in analytes …

Small molecule analysis by MALDI mass spectrometry

LH Cohen, AI Gusev - Analytical and bioanalytical chemistry, 2002 - Springer
This review focuses on the application of matrix assisted laser desorption/ionization (MALDI)
mass spectrometry to the characterization of molecules in the low mass range (< 1500 Da) …

MALDI imaging mass spectrometry: state of the art technology in clinical proteomics

J Franck, K Arafah, M Elayed, D Bonnel… - Molecular & Cellular …, 2009 - ASBMB
A decade after its inception, MALDI imaging mass spectrometry has become a unique
technique in the proteomics arsenal for biomarker hunting in a variety of diseases. At this …

Advances in MALDI mass spectrometry in clinical diagnostic applications

EWY Ng, MYM Wong, TCW Poon - Chemical Diagnostics: From Bench to …, 2014 - Springer
The concept of matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS)
was first reported in 1985. Since then, MALDI MS technologies have been evolving, and …

[HTML][HTML] MALDI Imaging mass spectrometry: current frontiers and perspectives in pathology research and practice

M Aichler, A Walch - Laboratory investigation, 2015 - Elsevier
MALDI Imaging mass spectrometry has entered the field of tissue-based research by
providing unique advantages for analyzing tissue specimen in an unprecedented detail. A …

Approaching MALDI molecular imaging for clinical proteomic research: current state and fields of application

S Rauser, SO Deininger, D Suckau… - Expert review of …, 2010 - Taylor & Francis
MALDI imaging mass spectrometry ('MALDI imaging') is an increasingly recognized
technique for biomarker research. After years of method development in the scientific …