Background Neuroinflammation has long been theorized to arise from exposures to fine
particulate matter and to be modulated when individuals experience chronic stress, both of …

Microglia are immune brain cells implicated in stress-related mental illnesses including
posttraumatic stress disorder (PTSD). Their role in the pathophysiology of PTSD, and on …

Background Chronically re-experiencing the memory of a traumatic event might cause a
glial response. This study examined whether glial activation would be associated with PTSD …

Abstract Gulf War Illness (GWI) is a chronic disorder affecting approximately 30% of the
veterans who served in the 1991 Gulf War. It is characterised by a constellation of symptoms …

Abstract World Trade Center (WTC) responders exposed to traumatic and environmental
stressors during rescue and recovery efforts have a high prevalence of chronic WTC-related …

Psychiatric disorders associated with psychosocial risk factors, including depression and
psychosis, have been shown to demonstrate increased microglia activity. Whilst preclinical …

One of the cellular markers of neuroinflammation is increased microglia activation,
characterized by overexpression of mitochondrial 18 kDa Translocator Protein (TSPO) …

There is emerging interest in understanding the role of the neuroimmune system in the
pathophysiology of neurodegenerative and psychiatric diseases. 1, 2 Neuroinflammation is …

Background Bacterial meningitis is a devastating central nervous system (CNS) infection
with acute and long-term neurological consequences, including cognitive impairment. The …

Despite well-known peripheral immune activation in posttraumatic stress disorder (PTSD),
there are no studies of brain immunologic regulation in individuals with PTSD.[11C] PBR28 …