We have examined the interactions of the six known rabbit neutrophil defensin antimicrobial
peptides with large unilamellar vesicles (LUV) made from various lipid mixtures based on …

Defensins comprise a family of broad‐spectrum antimicrobial peptides that are stored in the
cytoplasmic granules of mammalian neutrophils and Paneth cells of the small intestine …

Human antimicrobial neutrophil defensin HNP-2 has been shown to form large multimeric
pores in pure 1-palmitoyl-2-oleoyl phosphatidylglycerol (POPG) bilayers that lead to all-or …

Defensins constitute a major class of cationic antimicrobial peptides in mammals and
vertebrates, acting as effectors of innate immunity against infectious microorganisms. It is …

Defensins are cationic, cysteine-rich peptides (Mr= 3500-4000) found in the cytoplasmic
granules of neutrophils and macrophages. These peptides possess broad antimicrobial …

Defensins are small cationic antibacterial peptides that are abundant in polymorphonuclear
leukocytes from human and other sources (T. Ganz, M. Selsted, D. Szklarek, S. Harwig, K …

Defensins, small cationic polypeptides with antimicrobial and cytotoxic properties, are
among the principal constituents of cytoplasmic granules of mammalian neutrophils and …

α-Defensins are antimicrobial peptides with 29− 35 amino acid residues and cysteine-
stabilized amphiphilic, triple-stranded β-sheet structures. We used high-precision differential …

Antimicrobial proteins stored in lysosome-like granules of neutrophils and macrophages
probably play an important role in killing phagocytosed microbes after delivery to the …

Defensins induce ion channels in model lipid bilayers and permeabilize the membranes of
Escherichia coli. We investigated whether similar membrane-active events occur during …