Until recently, most envisaged atherosclerosis as a bland arterial collection of cholesterol,
complicated by smooth muscle cell accumulation. According to that concept, endothelial …

Until recently, most envisaged atherosclerosis as a bland arterial collection of cholesterol,
complicated by smooth muscle cell accumulation. According to that concept, endothelial …

The concept that inflammation governs atherosclerosis and its complications has provided a
new unifying hypothesis of the links between risk factors and the cellular and molecular …

Inflammation is now recognized as being pivotal in the pathogenesis of atherosclerosis. This
review highlights key concepts in our current understanding of the role of inflammation in the …

Atherosclerosis, formerly considered a bland lipid storage disease, actually involves an
ongoing inflammatory response. Recent advances in basic science have established a …

Inflammation constitutes a complex, highly conserved cascade of molecular and cellular
events. Inflammation has been labeled as “the fire within,” is highly regulated, and is critical …

Atherosclerosis is a chronic inflammatory process and both the innate and adaptive immune
systems 1 play central roles in its initiation and subsequent progression. 2 Experimental …

About half of the patients presenting with myocardial infarction do not have the classic risk
factors. This finding has stimulated a search for other factors that may be responsible and …

Despite considerable advances in reducing the global burden of atherosclerotic
cardiovascular disease by targeting conventional risk factors, significant residual risk …

Abstract Rudolph Virchow (1821–1902) recognized inflammation in histological
preparations of coronary arteries and proposed that inflammation plays a causal role in …