The purpose of the study was to design lipid-based-nanosuspensions (LNS) for Docetaxel
(DTX) without Tween 80 for clinical intravenous administration (iv). DTX-LNS were prepared …

The aim of the present study was to prepare, characterize, and evaluate solid lipid
nanoparticles (SLNs) containing docetaxel (DTX) to improve the efficacy of this …

The aim of this study was to design docetaxel-loaded nanostructured lipid carriers (DTX-
NLC) to reduce toxicity and improve therapeutic efficacy. Docetaxel-loaded nanostructured …

The aim of this study was to develop docetaxel-incorporated lipid nanoparticles (DTX-NPs)
to improve the pharmacokinetic behaviour of docetaxel (DTX) after oral and parenteral …

The purpose of this study was to develop two novel drug delivery systems based on
biodegradable docetaxel-lipid-based-nanosuspensions. The first one was poly (ethylene …

A well characterized Nanosomal Docetaxel Lipid Suspension (NDLS) formulation was
developed without using any detergent or toxic organic solvents to avoid hypersensitivity …

Background Metastasis causes the most breast cancer-related deaths in women. Here, we
investigated the antitumor effect of solid lipid nanoparticles (SLN-DTX) when used in the …

Docetaxel (DCX) is a second generation taxane. It is approved by the US Food and Drug
Administration for the treatment of various types of cancer, including breast, non-small cell …

Purpose A lipid-based, nanomicelle-loaded docetaxel (M-DOC) was designed and
characterized. Optical imaging was employed to evaluate the pharmacokinetics and …

Poor aqueous solubility is a serious problem for most chemotherapeutics. Docetaxel (DTX),
an inhibitor of microtubule depolymerization, is frequently used to treat many malignancies …