Quinolines, a perpetual, multipurpose scaffold in medicinal chemistry

P Yadav, K Shah - Bioorganic Chemistry, 2021 - Elsevier
Quinoline is a versatile pharmacophore, a privileged scaffold and an outstanding fused
heterocyclic compound with a wide range of pharmacological prospective such as …

Quinoline‐derivatives as privileged scaffolds for medicinal and pharmaceutical chemists: A comprehensive review

V Yadav, J Reang, V Sharma, J Majeed… - Chemical Biology & …, 2022 - Wiley Online Library
The quinoline scaffolds are privileged for their numerous biological activities in the
pharmaceutical field. This moiety constitutes a well‐known space in several marketed …

Therapeutic significance of quinolines: a patent review (2013-2015)

SMA Hussaini - Expert opinion on therapeutic patents, 2016 - Taylor & Francis
Introduction: Quinoline is a versatile bicyclic heterocyclic scaffold with immense therapeutic
potential. Some of the compounds containing quinoline nucleus are agents of choice for the …

Recent advances in the synthesis of biologically and pharmaceutically active quinoline and its analogues: a review

A Weyesa, E Mulugeta - RSC advances, 2020 - pubs.rsc.org
Recently, quinoline has become an essential heterocyclic compound due to its versatile
applications in the fields of industrial and synthetic organic chemistry. It is a vital scaffold for …

Recent advances in research of natural and synthetic bioactive quinolines

PY Chung, ZX Bian, HY Pun, D Chan… - Future medicinal …, 2015 - Taylor & Francis
Many natural products that consist of quinoline core are found to be bioactive and the
versatility of quinoline and its derivatives have attracted great attention in the field of drug …

A comprehensive review on the biological interest of quinoline and its derivatives

BS Matada, R Pattanashettar, NG Yernale - Bioorganic & Medicinal …, 2021 - Elsevier
Amongst heterocyclic compounds, quinoline is an advantaged scaffold that appears as a
significant assembly motif for the development of new drug entities. Quinoline and its …

Navigating the synthesis of quinoline hybrid molecules as promising anticancer agents

P Panda, S Chakroborty - ChemistrySelect, 2020 - Wiley Online Library
The emergence of drug resistance and low specificity with side effects are the significant
challenges in pharmaceutical sectors for control of cancer nowadays. Notwithstanding, this …

Current pharmaceutical aspects of synthetic quinoline derivatives

R Tabassum, M Ashfaq, H Oku - Mini Reviews in Medicinal …, 2021 - ingentaconnect.com
Quinoline derivatives are considered broad-spectrum pharmacological compounds that
exhibit a wide range of biological activities. Integration of quinoline moiety can improve its …

[HTML][HTML] Comprehensive review on current developments of quinoline-based anticancer agents

S Jain, V Chandra, PK Jain, K Pathak, D Pathak… - Arabian Journal of …, 2019 - Elsevier
Among heterocyclic compounds, quinoline scaffold has become an important construction
motif for the development of new drugs. Quinoline and its derivatives possess many types of …

[PDF][PDF] Biological activities of quinoline derivatives

S Kumar, S Bawa, H Gupta - Mini reviews in medicinal chemistry, 2009 - researchgate.net
Quinoline and its fused heterocyclic derivatives tested with diverse pharmacological activity
constitute an important class of compounds for new drug development. Therefore, many …