Impact of CRISPR-Cas9-based genome engineering in farm animals

P Singh, SA Ali - Veterinary Sciences, 2021 - mdpi.com
Humans are sorely over-dependent on livestock for their daily basic need of food in the form
of meat, milk, and eggs. Therefore, genetic engineering and transgenesis provide the …

[HTML][HTML] The transformational impact of site-specific DNA modifiers on biomedicine and agriculture

K Polkoff, JA Piedrahita - Animal Reproduction, 2018 - ncbi.nlm.nih.gov
The development of genetically modified livestock has been dependent on incremental
technological advances such as embryo transfer, homologous recombination, and somatic …

[PDF][PDF] CRISPR/Cas9 system: A broadly applicable tool for targeted genome engineering

HI Ahmad, M Yasir, MJ Ahmad - Journal Innovation Bio-Research, 2017 - researchgate.net
Targeted genome editing is a potent approach for genome engineering, perturbing and
interrogating the cellular systems. Current developments in genome editing are derived from …

The Evolution of Genome‐Editing Technologies

HI Ahmad, N Bibi, A Jabbar - OMICs‐based Techniques for …, 2024 - Wiley Online Library
The evolution of genome‐editing technologies refers to the development and advancement
of techniques used to modify the DNA of an organism. These technologies have rapidly …

Modulation of animal health through reverse genetics applications

HN Pawar, N Mitra, R Verma - Genomics and Biotechnological Advances in …, 2020 - Elsevier
In the present era of high throughput sequencing, genomic databases are piling up new
sequences everyday with very little known about their functions and phenotypic effects …

Genome editing of pigs for agriculture and biomedicine

H Yang, Z Wu - Frontiers in Genetics, 2018 - frontiersin.org
Pigs serve as an important agricultural resource and animal model in biomedical studies.
Efficient and precise modification of pig genome by using recently developed gene editing …

[HTML][HTML] Current status of production of transgenic livestock by genome editing technology

S Kim, DB Koo, MJ Kang - Journal of Animal Reproduction and …, 2019 - e-jarb.org
The Transgenic livestock can be useful for the production of disease-resistant animals, pigs
for xenotranplantation, animal bioreactor for therapeutic recombinant proteins and disease …

Generation of gene edited pigs

S Navarro-Serna, C Piñeiro-Silva, R Romar… - … Agriculture Reviews 57 …, 2022 - Springer
Abstract Background: The porcine species (Sus scrofa domesticus) has had a great impact
as a source of food worldwide, but also it is a very useful animal for biomedical applications …

Genome editing technologies drive the development of pig genetic improvement.

JJ Huang, CW Cao, GM Zheng, JG Zhao - Yi Chuan= Hereditas, 2017 - europepmc.org
Nuclease-mediated genome editing technologies contribute to the rapid advances in life
sciences via the ability to edit the genomes within living cells, and present a new era for …

Use of genome editing techniques to produce transgenic farm animals

AN Hay, K Farrell, CM Leeth, K Lee - Recent Advances in Animal Nutrition …, 2022 - Springer
Recombinant proteins are essential for the treatment and diagnosis of clinical human
ailments. The availability and biological activity of recombinant proteins is heavily influenced …