Red blood cell phenotyping is a sensitive technique for monitoring chronic myeloid leukaemia patients after T‐cell‐depleted bone marrow transplantation and after …

N Schaap, A Schattenberg, B Bär… - British journal of …, 2000 - Wiley Online Library
Fifteen consecutive patients with Philadelphia chromosome (Ph)‐positive chronic myeloid
leukaemia (CML) who relapsed from T‐cell‐depleted bone marrow transplantation (BMT) …

Quantitation of minimal residual disease in Philadelphia chromosome positive chronic myeloid leukaemia patients using real‐time quantitative RT‐PCR

Menskin, V De Locht, Schattenberg… - British journal of …, 1998 - Wiley Online Library
We used a recently developed system for real‐time quantitative polymerase chain reaction
(PCR) to determine residual disease in patients with chronic myeloid leukaemia. The …

Polymerase chain reaction is highly predictive of relapse in patients following T cell-depleted allogeneic bone marrow transplantation for chronic myeloid leukemia.

S Mackinnon, L Barnett, G Heller - Bone marrow transplantation, 1996 - europepmc.org
In chronic myeloid leukemia (CML) the polymerase chain reaction (PCR) can be used to
detect minimal residual disease after bone marrow transplantation (BMT). Previous studies …

Chimeric BCR-abl messenger RNA as a marker for minimal residual disease in patients transplanted for Philadelphia chromosome-positive acute lymphoblastic …

GB Gehly, EM Bryant, AM Lee, PG Kidd, ED Thomas - 1991 - ashpublications.org
We correlated polymerase chain reaction (PCR)-detectable BCR-abl fusion transcripts with
cytogenetic status in 24 patients with acute lymphocytic leukemia (ALL). Of 10 Philadelphia …

Quantification of minimal residual disease in patients with e1a2 BCR-ABL-positive acute lymphoblastic leukemia using a real-time RT-PCR assay

H Yokota, NH Tsuno, Y Tanaka, T Fukui, K Kitamura… - Leukemia, 2002 - nature.com
Using a real-time RT-PCR method, we analyzed the expression of e1a2 BCR-ABL mRNA in
bone marrow samples from 13 patients with e1a2 BCR-ABL-positive acute lymphoblastic …

A CD4+ T CELL CLONE SELECTED FROM A CML PATIENT AFTER DONOR LYMPHOCYTE INFUSION RECOGNIZES BCR-ABL BREAKPOINT PEPTIDES BUT …

E Zorn, E Orsini, CJ Wu, B Stein, A Chillemi… - …, 2001 - journals.lww.com
Background. In patients with chronic myelocytic leukemia (CML), the breakpoint cluster
region and fusion between the BCR and the c-ABL genes (BCR-ABL) oncogen product is a …

An international study to standardize the detection and quantitation of BCR-ABL transcripts from stabilized peripheral blood preparations by quantitative RT-PCR

MC Müller, G Saglio, F Lin, H Pfeifer, RD Press… - …, 2007 - haematologica.org
Due to the lack of comparability of BCR-ABL mRNA quantification results generated by
various methodologies in different laboratories, an international multicenter trial was started …

Frequent detection of minimal residual disease by use of the polymerase chain reaction in long-term survivors after bone marrow transplantation for chronic myeloid …

JM Pignon, T Henni, S Amselem, M Vidaud… - Leukemia, 1990 - europepmc.org
The polymerase chain reaction (PCR) allows the detection of minimal amounts of nucleic
sequences and has been successfully used to test for the chronic myeloid leukemia-specific …

Prediction of relapse by day 100 BCR-ABL quantification after allogeneic stem cell transplantation for chronic myeloid leukemia

V Asnafi, MT Rubio, E Delabesse, E Villar, F Davi… - Leukemia, 2006 - nature.com
Chronic myeloid leukemia (CML) relapse after allogeneic stem cell transplantation (SCT) is
a relatively frequent situation, which is correlated to disease status, time from diagnosis to …

Quantitative competitive reverse transcriptase-polymerase chain reaction for BCR-ABL on Philadelphia-negative leukaphereses allows the selection of low …

MT Corsetti, E Lerma, A Dejana, P Basta, R Ferrara… - Leukemia, 1999 - nature.com
Abstract The Philadelphia (Ph) translocation t (9; 22) results in the creation of the BCR-ABL
gene, which is now regarded as central to the mechanism that underlies the chronic phase …