Frequent detection of minimal residual disease by use of the polymerase chain reaction in long-term survivors after bone marrow transplantation for chronic myeloid …

JM Pignon, T Henni, S Amselem, M Vidaud… - Leukemia, 1990 - europepmc.org
The polymerase chain reaction (PCR) allows the detection of minimal amounts of nucleic
sequences and has been successfully used to test for the chronic myeloid leukemia-specific …

Quantitative competitive reverse transcriptase-polymerase chain reaction for BCR-ABL on Philadelphia-negative leukaphereses allows the selection of low …

MT Corsetti, E Lerma, A Dejana, P Basta, R Ferrara… - Leukemia, 1999 - nature.com
Abstract The Philadelphia (Ph) translocation t (9; 22) results in the creation of the BCR-ABL
gene, which is now regarded as central to the mechanism that underlies the chronic phase …

实时定量RT-PCR 监测慢性粒细胞白血病患者造血干细胞移植后bcr-abl mRNA 水平

秦亚溱, 李金兰, 主鸿鹄, 阮国瑞, 李玲娣, 张艳… - 中华血液学杂志, 2006 - cqvip.com
目的评价实时定量RT—PCR (Q—PCR) 技术用于监测慢性粒细胞白血病(CML)
患者异基因造血干细胞移植(HSCT) 疗效的意义. 方法采用基于TaqMan 探针的Q—PCR …

筑巢式PCR 检测白血病微量残留bcr/ablmRNA

郑维扬, 周淑芸, 王小琪, 孙竞 - 中华血液学杂志, 1994 - cqvip.com
采用逆转录-筑巢式聚合酶链反应技术检测33 例不同临床阶段的慢性粒细胞白血病及18
例急性淋巴细胞白血病患者的bcr/ablmRNA. 结果: 33 例CML 中31 例阳性其中21 …