Reactive oxygen species modulate the differentiation of neurons in clonal cortical cultures

M Tsatmali, EC Walcott, H Makarenkova… - Molecular and Cellular …, 2006 - Elsevier
Reactive oxygen species (ROS) are important regulators of intracellular signaling. We
examined the expression of ROS during rat brain development and explored their role in …

Regulation of neuronal development and function by ROS

MCW Oswald, N Garnham, ST Sweeney… - FEBS …, 2018 - Wiley Online Library
Reactive oxygen species (ROS) have long been studied as destructive agents in the context
of nervous system ageing, disease and degeneration. Their roles as signalling molecules …

From birth to death: A role for reactive oxygen species in neuronal development

C Wilson, E Muñoz-Palma… - Seminars in cell & …, 2018 - Elsevier
Historically, ROS have been considered toxic molecules, especially when their intracellular
concentration reaches high values. However, physiological levels of ROS support crucial …

Reactive oxygen species: angels and demons in the life of a neuron

K Biswas, K Alexander, MM Francis - NeuroSci, 2022 - mdpi.com
Reactive oxygen species (ROS) have emerged as regulators of key processes supporting
neuronal growth, function, and plasticity across lifespan. At normal physiological levels, ROS …

Newborn neurons acquire high levels of reactive oxygen species and increased mitochondrial proteins upon differentiation from progenitors

M Tsatmali, EC Walcott, KL Crossin - Brain research, 2005 - Elsevier
A population of embryonic rat cortical cells cultured in the presence of FGF2 and having
neuronal morphology expressed higher levels of reactive oxygen species (ROS) than did …

Reactive oxygen species and the neuronal fate

KAM Kennedy, SDE Sandiford, IS Skerjanc… - Cellular and Molecular …, 2012 - Springer
Aberrant or elevated levels of reactive oxygen species (ROS) can mediate deleterious
cellular effects, including neuronal toxicity and degeneration observed in the etiology of a …

ROS Produced by NOX2 Controls In Vitro Development of Cerebellar Granule Neurons Development

M Olguín-Albuerne, J Morán - ASN neuro, 2015 - journals.sagepub.com
Reactive oxygen species (ROS) act as signaling molecules that regulate nervous system
physiology. ROS have been related to neural differentiation, neuritogenesis, and …

Signaling by reactive oxygen species in the nervous system

P Maher*, D Schubert - Cellular and Molecular Life Sciences CMLS, 2000 - Springer
Free radicals and reactive oxygen species (ROS) are involved in a variety of different
cellular processes ranging from apoptosis and necrosis to cell proliferation and …

Endogenous reactive oxygen species are essential for proliferation of neural stem/progenitor cells

M Yoneyama, K Kawada, Y Gotoh, T Shiba… - Neurochemistry …, 2010 - Elsevier
It is widely thought that accumulation of reactive oxygen species (ROS) causes injury to
cells. In this study, we investigated the effect of endogenous ROS on the proliferation of …

Reactive oxygen species induce different cell death mechanisms in cultured neurons

A Valencia, J Morán - Free Radical Biology and Medicine, 2004 - Elsevier
Apoptosis is characterized by chromatin condensation, phosphatidylserine translocation,
and caspase activation. Neuronal apoptotic death involves the participation of reactive …