Differential levels of inflammatory and neuroendocrine markers in the hippocampus and anterior cingulate cortex of bipolar disorder subjects: a post-mortem study

C Nascimento, PV Nunes, CK Suemoto… - Brain, behavior, and …, 2020 - Elsevier
Bipolar disorder (BD) is a severe and recurrent neuropsychiatric illness that causes high
rates of disability, with onset frequently during adolescence and early adulthood (Barnett …

The relationship of neuropsychiatric symptoms with inflammatory markers in the hippocampus and cingulate cortex of bipolar disorder subjects: A post-mortem study

C Nascimento, PV Nunes, REP Leite… - Journal of Psychiatric …, 2024 - Elsevier
Increased levels of inflammation markers have been found in the peripheral tissue of
individuals with bipolar disorder (BD), especially during mood episodes. Previous studies …

Neurobiology of bipolar disorder: abnormalities on cognitive and cortical functioning and biomarker levels

AS de Sá, C Campos, N BF Rocha… - CNS & Neurological …, 2016 - ingentaconnect.com
Bipolar disorder (BD) affects 1 to 1.5% of the world population and consists of at least one
manic episode (or hypomanic) associated with depressive episodes, interspersed with …

Neurobiological Underpinnings of Bipolar Disorder and Its Treatment

B Singh, F Romo-Nava, AB Cuellar-Barboza - Frontiers in psychiatry, 2021 - frontiersin.org
Bipolar disorder (BD) is a severe mental illness, with significant morbidity, and is a leading
cause of disability. There have been significant advancements in the biological …

[HTML][HTML] Inflammatory biomarkers, cognitive functioning, and brain imaging abnormalities in bipolar disorder: A systematic review

A Mario, L Ivana, M Anita, M Silvio… - Clinical …, 2024 - ncbi.nlm.nih.gov
Objective Recent studies have pointed to neuroinflammation and neurotrophic factors as
crucial mediators in the pathophysiology origins of mood disorders. The aim of this review is …

Inflammation as a mechanism of bipolar disorder neuroprogression

T Barichello, VV Giridharan, G Bhatti, P Sayana… - Bipolar Disorder: From …, 2021 - Springer
Bipolar disorder (BD) is a severe, debilitating psychiatric condition with onset in
adolescence or young adulthood and often follows a relapsing and remitting course …

Peripheral levels of C-reactive protein, tumor necrosis factor-α, interleukin-6, and interleukin-1β across the mood spectrum in bipolar disorder: a meta-analysis of …

M Solmi, MS Sharma, EF Osimo, M Fornaro… - Brain, Behavior, and …, 2021 - Elsevier
Importance It is unclear whether differences exist in the magnitude and variability of pro-
inflammatory mediators in the different phases of bipolar disorder (BD) and among subjects …

Cytokines in bipolar disorder vs. healthy control subjects: a systematic review and meta-analysis

K Munkholm, JV Braüner, LV Kessing… - Journal of psychiatric …, 2013 - Elsevier
Background Bipolar disorder may be associated with peripheral immune system
dysfunction; however, results in individual studies are conflicting. Our aim was to …

Inflammation as a neurobiological substrate of cognitive impairment in bipolar disorder: evidence, pathophysiology and treatment implications

JD Rosenblat, E Brietzke, RB Mansur… - Journal of affective …, 2015 - Elsevier
Background Bipolar disorder (BD) has been associated with cognitive impairment during
depressed, manic and euthymic periods. Inflammation has been shown to be involved in the …

Proinflammatory cytokines predict brain metabolite concentrations in the anterior cingulate cortex of patients with bipolar disorder

S Poletti, MG Mazza, B Vai, C Lorenzi… - Frontiers in …, 2020 - frontiersin.org
Bipolar disorder (BD) is a severe psychiatric illness characterized by abnormalities in the
immune/inflammatory function and in brain metabolism. Evidences suggest that …