Diagnostics and treatment of nerve agent poisoning—current status and future developments

N Amend, KV Niessen, T Seeger, T Wille… - Annals of the New …, 2020 - Wiley Online Library
Although 193 states have committed to the Chemical Weapons Convention and 98% of the
declared chemical weapons stockpiles have been destroyed so far, nerve agent poisoning …

Therapy for acute nerve agent poisoning: An update

J Newmark - Neurology: Clinical Practice, 2019 - AAN Enterprises
Purpose of review Acute nerve agent poisoning was last reviewed in the neurology literature
in 2004. As neurologists may expect to be called upon by non-neurologist colleagues as …

Treatment of nerve agent poisoning

H Thiermann, N Aurbek, F Worek - 2016 - books.rsc.org
1.1 Introduction therapy of nerve agent poisoning is a challenge for clinical toxicologists,
specialists in intensive care units, medical doctors and all other medical personnel. the …

Nerve agents: pathophysiology and treatment of poisoning

J Newmark - Seminars in neurology, 2004 - thieme-connect.com
Nerve agents, the deadliest of the classical chemical warfare agents, primarily function as
acetylcholinesterase inhibitors and cause a rapidly progressive cholinergic crisis. Because …

Limitations and challenges in treatment of acute chemical warfare agent poisoning

H Thiermann, F Worek, K Kehe - Chemico-biological interactions, 2013 - Elsevier
Recent news from Syria on a possible use of chemical warfare agents made the headlines.
Furthermore, the motivation of terrorists to cause maximal harm shifts these agents into the …

Evolution of and perspectives on therapeutic approaches to nerve agent poisoning

P Masson - Toxicology letters, 2011 - Elsevier
After more than 70 years of considerable efforts, research on medical defense against nerve
agents has come to a standstill. Major progress in medical countermeasures was achieved …

Nerve agents

J Newmark - The neurologist, 2007 - journals.lww.com
Background: Nerve agents, the deadliest of the classic chemical warfare agents, primarily
function as acetylcholinesterase inhibitors and cause a rapidly progressive cholinergic …

Therapy for nerve agent poisoning

J Newmark - Archives of neurology, 2004 - jamanetwork.com
Neurologists need to familiarize themselves with nerve agents, the most toxic of the
chemical warfare agents. Their mode of action lies within the nervous system, and …

Future considerations for the medical management of nerve-agent intoxication

P Aas - Prehospital and disaster medicine, 2003 - cambridge.org
The use of chemical warfare agents against civilians and unprotected troops in international
conflicts or by terrorists against civilians is considered to be a real threat, particularly …

Chemical warfare: nerve agent poisoning

CP Holstege, M Kirk, FR Sidell - Critical care clinics, 1997 - Elsevier
Nerve agents are organophosphate anticholinesterases that have commanded a great deal
of media attention in the past decade. Their military use by Iraq against Iran and the Kurds …