To develop a tool to obtain a high level of gene expression specifically in endothelial cells
(ECs), we assessed enhancer activity of fragments in the first intron of the VE-cadherin gene …

Vascular endothelial-cadherin (VE-cadherin) is a calcium-dependent adhesive molecule,
exclusively and constitutively expressed in endothelial cells. Analysis of the VE-cadherin …

Hematopoietic stem cells (HSCs) and endothelial progenitors arise from a common
embryonic precursor. However, these populations diverge prior to the onset of definitive …

Background Endothelial differentiation occurs during normal vascular development in the
developing embryo. This process is recapitulated in the adult when endothelial progenitor …

Vascular endothelial–cadherin (VE–cadherin) is exclusively expressed in endothelial cells
and is strictly located at cell-to-cell junctions. As the other members of the cadherin family …

Human embryonic stem cell line WA0 1 was genetically modified using zinc-finger
nucleases and the PiggyBac/transponson system to introduce a fluorescence reporter for VE …

Vascular endothelial (VE)-cadherin is exclusively expressed at interendothelial junctions of
normal and tumour vessels. In this report, we characterized the transcriptional activity of the …

Hematopoietic stem cells (HSCs) arise first in the third week of human ontogeny inside yolk
sac developing blood vessels, and independently, from the wall of the embryonic aorta and …

The identification of novel endothelial-derived genes is important in the study of
angiogenesis, and may have potential uses in cancer diagnosis and treatment. We …

Accumulating evidence supports the exis-tence of a common hematopoietic/endothelial
stem cell during early embryonic development, 1 and recent studies suggest that cells with …