PTX3 as a paradigm for the interaction of pentraxins with the complement system
A Inforzato, A Doni, I Barajon, R Leone… - Seminars in …, 2013 - Elsevier
Pentraxins are highly conserved components of the humoral arm of innate immunity. They
include the short pentraxins C reactive protein (CRP) and serum amyloid P component …
include the short pentraxins C reactive protein (CRP) and serum amyloid P component …
Pentraxins in innate immunity: from C-reactive protein to the long pentraxin PTX3
Pentraxins are a family of multimeric pattern-recognition proteins highly conserved in
evolution. Based on the primary structure of the subunit, the pentraxins are divided into two …
evolution. Based on the primary structure of the subunit, the pentraxins are divided into two …
Pentraxins: multifunctional proteins at the interface of innate immunity and inflammation
L Deban, B Bottazzi, C Garlanda, YM de la Torre… - Biofactors, 2009 - Wiley Online Library
Pentraxins are a family of multimeric pattern recognition proteins highly conserved in
evolution. On the basis of the primary structure of the protomer, pentraxins are divided into …
evolution. On the basis of the primary structure of the protomer, pentraxins are divided into …
Pentraxins in innate immunity: lessons from PTX3
The innate immune system constitutes the first line of defence against microorganisms and
plays a primordial role in the activation and regulation of adaptive immunity. The innate …
plays a primordial role in the activation and regulation of adaptive immunity. The innate …
Interactions of the humoral pattern recognition molecule PTX3 with the complement system
The innate immune system comprises a cellular and a humoral arm. The long pentraxin
PTX3 is a fluid phase pattern recognition molecule, which acts as an essential component of …
PTX3 is a fluid phase pattern recognition molecule, which acts as an essential component of …
The long pentraxin PTX3 as a key component of humoral innate immunity and a candidate diagnostic for inflammatory diseases
The innate immune system is composed of a cellular arm and a humoral arm. Components
of the humoral arm include members of the complement cascade and soluble pattern …
of the humoral arm include members of the complement cascade and soluble pattern …
Pentraxins as a key component of innate immunity
B Bottazzi, C Garlanda, G Salvatori, P Jeannin… - Current opinion in …, 2006 - Elsevier
Pentraxins are a complex superfamily of multifunctional molecules characterized by a
multimeric structure. C-reactive protein and pentraxin 3 (PTX3) are prototypic molecules of …
multimeric structure. C-reactive protein and pentraxin 3 (PTX3) are prototypic molecules of …
Regulation of the complement system by pentraxins
K Haapasalo, S Meri - Frontiers in immunology, 2019 - frontiersin.org
The functions of pentraxins, like C-reactive protein (CRP), serum amyloid protein P (SAP)
and pentraxin-3 (PTX3), are to coordinate spatially and temporally targeted clearance of …
and pentraxin-3 (PTX3), are to coordinate spatially and temporally targeted clearance of …
Pentraxins in complement activation and regulation
The complement is the first line of immune defense system involved in elimination of
invading pathogens and dying host cells. Its activation is mainly triggered by immune …
invading pathogens and dying host cells. Its activation is mainly triggered by immune …
The long pentraxin PTX3: a paradigm for humoral pattern recognition molecules
A Mantovani, S Valentino, S Gentile… - Annals of the New …, 2013 - Wiley Online Library
Pattern recognition molecules (PRMs) are components of the humoral arm of innate
immunity; they recognize pathogen‐associated molecular patterns (PAMP) and are …
immunity; they recognize pathogen‐associated molecular patterns (PAMP) and are …