Chrysanthemi Flos extract alleviated acetaminophen-induced rat liver injury via inhibiting oxidative stress and apoptosis based on network pharmacology analysis

Y Zhou, C Wang, J Kou, M Wang, X Rong… - Pharmaceutical …, 2021 - Taylor & Francis
Context Acetaminophen (APAP) overdose is the leading cause of drug-induced liver injury.
Bianliang ziyu, a variety of Chrysanthemum morifolium Ramat.(Asteraceae), has potential …

[HTML][HTML] Chrysanthemum extract attenuates hepatotoxicity via inhibiting oxidative stress in vivo and in vitro

Z Tian, H Jia, Y Jin, M Wang, J Kou… - Food & Nutrition …, 2019 - ncbi.nlm.nih.gov
Background 'Bianliang ziyu', a famous chrysanthemum variety commonly planted in Kaifeng,
China, is often consumed by local residents. However, the hepatoprotective effects of …

Licochalcone A upregulates Nrf2 antioxidant pathway and thereby alleviates acetaminophen-induced hepatotoxicity

H Lv, Q Xiao, J Zhou, H Feng, G Liu, X Ci - Frontiers in Pharmacology, 2018 - frontiersin.org
Acetaminophen (APAP) overdose-induced fatal hepatotoxicity is majorly characterized by
overwhelmingly increased oxidative stress while enhanced nuclear factor-erythroid 2 …

Diacerein ameliorates acetaminophen hepatotoxicity in rats via inhibiting HMGB1/TLR4/NF-κB and upregulating PPAR-γ signal

GA Mohamed Kamel, E Harahsheh… - Molecular Biology Reports, 2022 - Springer
Background Acetaminophen (APAP) is a worldwide antipyretic as well as an analgesic
medication. It has been extensively utilized during the outbreak of coronavirus 2019 (COVID …

Bazhen decoction protects against acetaminophen induced acute liver injury by inhibiting oxidative stress, inflammation and apoptosis in mice

E Song, J Fu, X Xia, C Su, Y Song - PLoS One, 2014 - journals.plos.org
Bazhen decoction is a widely used traditional Chinese medicinal decoction, but the scientific
validation of its therapeutic potential is lacking. The objective of this study was to investigate …

[HTML][HTML] Veronica persica ameliorates acetaminophen-induced murine hepatotoxicity via attenuating oxidative stress and inflammation

W Tian, J Zhao, MK Kim, HJ Tae, IS Kim, D Ahn… - Biomedicine & …, 2023 - Elsevier
Excess acetaminophen (APAP) commonly causes severe acute liver injury (ALI),
characterized by oxidative stress, pro-inflammatory responses, and hepatocyte damage …

[HTML][HTML] Hepatoprotective effect of Citrus aurantium L. against APAP-induced liver injury by regulating liver lipid metabolism and apoptosis

Y Shu, D He, W Li, M Wang, S Zhao, L Liu… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
Acetaminophen (APAP) refers to a medication used to manage pain and fever symptoms,
but it always causes liver injury when overdosed. Zhishi, dried young fruit of Citrus …

Effects of the Total Saponins from Rosa laevigata Michx Fruit against Acetaminophen-Induced Liver Damage in Mice via Induction of Autophagy and Suppression of …

D Dong, L Xu, X Han, Y Qi, Y Xu, L Yin, K Liu, J Peng - Molecules, 2014 - mdpi.com
The effect of the total saponins from Rosa laevigata Michx fruit (RLTS) against
acetaminophen (APAP)-induced liver damage in mice was evaluated in the present paper …

The protective effect of aspirin eugenol ester on paraquat-induced acute liver injury rats

ZD Zhang, YJ Yang, XW Liu, Z Qin, SH Li… - Frontiers in Medicine, 2020 - frontiersin.org
Aspirin eugenol ester (AEE) possesses anti-inflammatory and anti-oxidative effects. The
study was conducted to evaluate the protective effect of AEE on paraquat-induced acute …

Integrated strategy of network pharmacology, molecular docking, HPLC-DAD and mice model for exploring active ingredients and pharmacological mechanisms of …

Y Jiang, M Zhong, H Zhan, X Tao, Y Zhang… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Penthorum chinense Pursh (PCP, Saxifragaceae)
is an edible plant and frequently-used Chinese herbal medicine, and is commonly used as …