Previous studies have shown that drugs which block the reuptake of catecholamine
neurotransmitters improve impulse control in diseases such as attention deficit hyperactivity …

Rationale Atomoxetine, reboxetine and methylphenidate all act at the noradrenaline
transporter (NAT) and atomoxetine and methylphenidate are licensed for the treatment of …

Rationale High levels of impulsivity are a core symptom of psychiatric disorders such as
ADHD, mania, personality disorders and drug addiction. The effectiveness of drugs targeting …

Rationale Impulsivity is associated with a number of psychiatric disorders, most notably
attention deficit/hyperactivity disorder (ADHD). Drugs that augment catecholamine function …

Impulsivity is a pathological symptom in several psychiatric disorders, underscoring the
need for animal models of impulsive action to develop a brief screening method for novel …

Aberrant impulsivity is found in a number of psychiatric disorders including attention deficit
hyperactivity disorder (ADHD). The 5-choice serial reaction time task (5-CSRTT) is a …

Higher impulsivity is a risk factor for criminal involvement, substance abuse, and suicide.
However, only a few drugs are clinically available for the treatment of deficient impulse …

Deficits in attention and response inhibition are apparent across several neurodegenerative
and neuropsychiatric disorders for which current pharmacotherapy is inadequate. The 5 …

Rationale Psychomotor stimulant drugs such as methylphenidate and amphetamine
decrease impulsive behaviour in attention deficit hyperactivity disorder patients by unknown …

Animal models are making an increasing contribution to our understanding of the
psychology and brain mechanisms underlying behavioral inhibition and impulsivity. The aim …