Relationship between two forms of impulsivity in mice at baseline and under acute and sub-chronic atomoxetine treatment

M Kyriakidou, M Caballero-Puntiverio… - Progress in Neuro …, 2023 - Elsevier
Rationale Impulsivity is a symptom of various mental disorders, including attention deficit
hyperactivity disorder (ADHD), bipolar disorder, and addiction. Impulsivity is not a unitary …

Acute and subchronic effects of buspirone on attention and impulsivity in the five-choice serial reaction time task in rats

CL Lu, YC Ku, SM Lo, CH Peng, CS Tung, YW Lin… - Neuroscience …, 2013 - Elsevier
Abstract Serotonin (5-HT)-related drugs are extensively employed in the treatment of mental
disorders. However, the roles of the central serotonergic system in impulse control over …

Individual differences in impulsive action reflect variation in the cortical serotonin 5-HT2A receptor system

LHL Fink, NC Anastasio, RG Fox, KC Rice… - …, 2015 - nature.com
Impulsivity is an important feature of multiple neuropsychiatric disorders, and individual
variation in the degree of inherent impulsivity could play a role in the generation or …

Sub-optimal performance in the 5-choice serial reaction time task in rats was sensitive to methylphenidate, atomoxetine and d-amphetamine, but unaffected by the …

NE Paterson, J Ricciardi, C Wetzler, T Hanania - Neuroscience research, 2011 - Elsevier
Prefrontal cortical dopamine (DA) and norepinephrine (NE) are implicated in multiple
aspects of cognitive function assessed via the 5-choice serial reaction time task (5-CSRTT) …

Behavioral stimulation without alteration of β and 5-HT receptors and adenylate cyclase activity in rat brain after chronic sertraline administration

C Tadokoro, Y Kiuchi, Y Yamazaki, K Nara… - …, 1997 - Springer
Abstract Effects of chronic treatment with selective 5-HT reuptake inhibitors (SSRIs) on the
monoaminergic functions have not been much investigated in compared with tricyclic …

Sensitivity of the five-choice serial reaction time task to the effects of various psychotropic drugs in Sprague-Dawley rats

TA Paine, HC Tomasiewicz, K Zhang… - Biological psychiatry, 2007 - Elsevier
BACKGROUND: Attentional deficits accompany many psychiatric disorders, underscoring
the need for rodent models of attention to screen novel therapeutic agents and characterize …

The neuropharmacology of impulsive behaviour

T Pattij, LJMJ Vanderschuren - Trends in pharmacological sciences, 2008 - cell.com
Impulsivity is a heterogenous phenomenon encompassing several behavioural phenomena
that can be dissociated neuroanatomically as well as pharmacologically. Impulsivity is …

Separation of drug effects on timing and behavioral inhibition by increased stimulus control.

JL Wiley, AD Compton, KM Golden - Experimental and clinical …, 2000 - psycnet.apa.org
Impulsive behavior may represent, in part, a failure of behavioral inhibition (the ability to
delay or inhibit a response). In this study, use of a multiple signaled–unsignaled differential …

Fractionating impulsivity: contrasting effects of central 5-HT depletion on different measures of impulsive behavior

CA Winstanley, JW Dalley, DEH Theobald… - …, 2004 - nature.com
Reducing levels of 5-HT in the central nervous system has been associated with increases
in impulsive behavior. However, the impulsivity construct describes a wide range of …

Investigating glutamatergic mechanism in attention and impulse control using rats in a modified 5-choice serial reaction time task

A Benn, ESJ Robinson - PloS one, 2014 - journals.plos.org
The 5-choice serial reaction time task (5CSRTT) has been widely used to study attention
and impulse control in rodents. In order to mimic cognitive impairments in psychiatry, one …