Long-acting beta-agonists and their association with inhaled corticosteroids in COPD

L Fuso, N Mores, S Valente, M Malerba… - Current medicinal …, 2013 - ingentaconnect.com
Inhaled bronchodilators, including beta2-agonists and antimuscaric receptor antagonists,
are the mainstay of pharmacotherapy in chronic obstructive pulmonary disease (COPD). The …

[HTML][HTML] Long-acting beta-agonists in the management of chronic obstructive pulmonary disease: current and future agents

DP Tashkin, LM Fabbri - Respiratory research, 2010 - Springer
Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow
limitation and debilitating symptoms. For patients with moderate-to-severe COPD, long …

Inhaled muscarinic acetylcholine receptor antagonists for treatment of COPD

P Montuschi, F Macagno, S Valente… - Current Medicinal …, 2013 - ingentaconnect.com
Bronchodilators, generally administered via metered dose or dry powder inhalers, are the
mainstays of pharmacological treatment of stable COPD. Inhaled long-acting beta-agonists …

Long-acting β2-agonists (LABA) in chronic obstructive pulmonary disease: efficacy and safety

A Rossi, S Khirani, M Cazzola - International journal of chronic …, 2008 - Taylor & Francis
COPD is characterized by progressive airflow obstruction which does not fully reverse to
inhaled or oral pharmacotherapy. The management of patients with COPD has taken a …

Mono-and combination therapy of long-acting bronchodilators and inhaled corticosteroids in advanced COPD

JA Ohar, JF Donohue - Seminars in respiratory and critical care …, 2010 - thieme-connect.com
Beta-2 adrenergic agonists are sympathomimetic agents that stimulate bronchodilation by
activation of adenyl cyclase to produce cyclic 3′ 5′ adenosine monophosphate (AMP) …

Why use long acting bronchodilators in chronic obstructive lung diseases? An extensive review on formoterol and salmeterol

P Santus, D Radovanovic, P Paggiaro, A Papi… - European Journal of …, 2015 - Elsevier
Long-acting β 2-adrenoceptor agonists, formoterol and salmeterol, represent a milestone in
the treatments of chronic obstructive lung diseases. Although no specific indications …

Long-acting β2-adrenoceptor agonists or tiotropium bromide for patients with COPD: is combination therapy justified?

RC Tennant, EM Erin, PJ Barnes, TT Hansel - Current opinion in …, 2003 - Elsevier
Bronchodilators are the mainstay of therapy for patients with established chronic obstructive
pulmonary disease (COPD) but, at present, the majority of patients use short-acting agents …

The use of long acting β2-agonists, alone or in combination with inhaled corticosteroids, in Chronic Obstructive Pulmonary Disease (COPD): A risk–benefit analysis

AC Cave, MM Hurst - Pharmacology & therapeutics, 2011 - Elsevier
Chronic Obstructive Pulmonary Disease (COPD) is a slowly progressive, largely non-
reversible pulmonary disease which is characterised by airflow limitation. It is one of the few …

Alternative mechanisms for long-acting β2-adrenergic agonists in COPD

M Johnson, S Rennard - Chest, 2001 - Elsevier
β 2-Adrenergic agonists are commonly used asbronchodilators to treat patients with COPD.
In addition to prolongedbronchodilation, long-acting β 2-agonists (LABAs) exertother effects …

Pharmacological basis and scientific rationale underlying the targeted use of inhaled corticosteroid/long-acting β2-adrenergic agonist combinations in chronic …

G Pelaia, CC Muzzio, A Vatrella, R Maselli… - Expert Opinion on …, 2015 - Taylor & Francis
Introduction: Chronic obstructive pulmonary disease (COPD) is a complex respiratory
disorder, whose medical and socioeconomic burden as one of the main causes of morbidity …