The mitochondrion is a double membrane structured organelle involved in a variety of
regulatory functions such as calcium signaling, production of adenosine triphosphate …

Spinal cord injury (SCI) is characterized by an initial trauma followed by a progressive
cascade of damage referred to as secondary injury. A hallmark of secondary injury is …

Traumatic brain injury is a complicated disease to treat due to the complex multi-factorial
secondary injury cascade that is initiated following the initial impact. This secondary injury …

Traumatic brain injury (TBI) is still the leading cause of disability in young adults worldwide.
The major mechanisms–diffuse axonal injury, cerebral contusion, ischemic neurological …

The enduring cognitive deficits and histopathology associated with traumatic brain injury
(TBI) may arise from damage to mitochondrial populations, which initiates the metabolic …

Mitochondria are dynamic organelles responsible for cellular energy production. Besides,
regulating energy homeostasis, mitochondria are responsible for calcium homeostasis …

Traumatic injury to the mammalian spinal cord is a highly dynamic process characterized by
a complex pattern of pervasive and destructive biochemical and pathophysiological events …

Central nervous system (CNS) diseases, both traumatic and neurodegenerative, are
characterized by impaired mitochondrial bioenergetics and often disturbed mitochondrial …

Therapeutic interventions directly targeting processes and mechanisms responsible for
mitochondrial dysfunction, may offer neuroprotection in brain-injured patients. The …

Traumatic brain injury (TBI) represents a leading cause of death and morbidity, as well as a
considerable social and economical burden in western countries, and has thus emerged as …