[HTML][HTML] Stimulation of CGRP-expressing neurons in the medial cerebellar nucleus induces light and touch sensitivity in mice
M Wang, WC Castonguay, TL Duong, MW Huebner… - Neurobiology of …, 2022 - Elsevier
Calcitonin gene-related peptide (CGRP) is considered a major player in migraine
pathophysiology. However, the location and mechanisms of CGRP actions in migraine are …
pathophysiology. However, the location and mechanisms of CGRP actions in migraine are …
PACAP induces light aversion in mice by an inheritable mechanism independent of CGRP
A Kuburas, BN Mason, B Hing, AS Wattiez… - Journal of …, 2021 - Soc Neuroscience
The neuropeptides CGRP (calcitonin gene-related peptide) and PACAP (pituitary adenylate
cyclase-activating polypeptide) have emerged as mediators of migraine, yet the potential …
cyclase-activating polypeptide) have emerged as mediators of migraine, yet the potential …
[HTML][HTML] Genetic enhancement of calcitonin gene-related Peptide-induced central sensitization to mechanical stimuli in mice
BM de Prado, DL Hammond, AF Russo - The journal of pain, 2009 - Elsevier
Calcitonin gene-related peptide (CGRP) is a key player in migraine. To address the role of
CGRP in mechanical allodynia, which is a common feature of migraine, we used CGRP …
CGRP in mechanical allodynia, which is a common feature of migraine, we used CGRP …
Peripherally administered calcitonin gene–related peptide induces spontaneous pain in mice: Implications for migraine
BJ Rea, AS Wattiez, JS Waite, WC Castonguay… - Pain, 2018 - journals.lww.com
Migraine is the third most common disease in the world (behind dental caries and tension-
type headache) with an estimated global prevalence of 15%, yet its etiology remains poorly …
type headache) with an estimated global prevalence of 15%, yet its etiology remains poorly …
Sensitization of calcitonin gene-related peptide receptors by receptor activity-modifying protein-1 in the trigeminal ganglion
Z Zhang, CS Winborn, BM de Prado… - Journal of …, 2007 - Soc Neuroscience
The neuropeptide calcitonin gene-related peptide (CGRP) from the trigeminal ganglion has
been established as a key player in the pathogenesis of migraine. In this study, we provide …
been established as a key player in the pathogenesis of migraine. In this study, we provide …
[HTML][HTML] Antagonism of CGRP receptor: central and peripheral mechanisms and mediators in an animal model of chronic migraine
R Greco, C Demartini, M Francavilla, AM Zanaboni… - Cells, 2022 - mdpi.com
Calcitonin-gene-related peptide (CGRP) plays a key role in migraine pathophysiology and
more specifically in the mechanisms underlying peripheral and central sensitization. Here …
more specifically in the mechanisms underlying peripheral and central sensitization. Here …
CGRP and migraine: could PACAP play a role too?
Migraine is a debilitating neurological disorder that affects about 12% of the population. In
the past decade, the role of the neuropeptide calcitonin gene-related peptide (CGRP) in …
the past decade, the role of the neuropeptide calcitonin gene-related peptide (CGRP) in …
Calcitonin gene-related peptide (CGRP): a new target for migraine
AF Russo - Annual review of pharmacology and toxicology, 2015 - annualreviews.org
Migraine is a neurological disorder that manifests as a debilitating headache associated
with altered sensory perception. The neuropeptide calcitonin gene-related peptide (CGRP) …
with altered sensory perception. The neuropeptide calcitonin gene-related peptide (CGRP) …
Dural calcitonin gene-related peptide produces female-specific responses in rodent migraine models
A Avona, C Burgos-Vega, MD Burton… - Journal of …, 2019 - Soc Neuroscience
Migraine is the second leading cause for disability worldwide and the most common
neurological disorder. It is also three times more common in women; reasons for this sex …
neurological disorder. It is also three times more common in women; reasons for this sex …
CGRP in animal models of migraine
AS Wattiez, M Wang, AF Russo - Calcitonin Gene-Related Peptide (CGRP …, 2019 - Springer
With the approval of calcitonin gene-related peptide (CGRP) and CGRP receptor
monoclonal antibodies by the Federal Drug Administration, a new era in the treatment of …
monoclonal antibodies by the Federal Drug Administration, a new era in the treatment of …