Inertial microfluidics for continuous particle separation in spiral microchannels

SS Kuntaegowdanahalli, AAS Bhagat, G Kumar… - Lab on a Chip, 2009 - pubs.rsc.org
In this work we report on a simple inertial microfluidic device that achieves continuous multi-
particle separation using the principle of Dean-coupled inertial migration in spiral …

Spiral microchannel with rectangular and trapezoidal cross-sections for size based particle separation

G Guan, L Wu, AA Bhagat, Z Li, PCY Chen, S Chao… - Scientific reports, 2013 - nature.com
The paper reports a new method for three-dimensional observation of the location of
focused particle streams along both the depth and width of the channel cross-section in …

Continuous particle separation in spiral microchannels using dean flows and differential migration

AAS Bhagat, SS Kuntaegowdanahalli, I Papautsky - Lab on a Chip, 2008 - pubs.rsc.org
Microparticle separation and concentration based on size has become indispensable in
many biomedical and environmental applications. In this paper we describe a passive …

Inertial microfluidics for continuous particle filtration and extraction

AAS Bhagat, SS Kuntaegowdanahalli… - Microfluidics and …, 2009 - Springer
In this paper, we describe a simple passive microfluidic device with rectangular
microchannel geometry for continuous particle filtration. The design takes advantage of …

Spiral microchannel with ordered micro-obstacles for continuous and highly-efficient particle separation

S Shen, C Tian, T Li, J Xu, SW Chen, Q Tu, MS Yuan… - Lab on a Chip, 2017 - pubs.rsc.org
Controllable manipulation of fluid flow is crucial for efficient particle separation, which is
associated with plenty of biomedical and industrial applications. Microfluidic technologies …

Tuning particle inertial separation in sinusoidal channels by embedding periodic obstacle microstructures

H Cha, H Fallahi, Y Dai, S Yadav, S Hettiarachchi… - Lab on a Chip, 2022 - pubs.rsc.org
Inertial microfluidics functions solely based on the fluid dynamics at relatively high flow
speed. Thus, channel geometry is the critical design parameter that contributes to the …

Continuous inertial microparticle and blood cell separation in straight channels with local microstructures

Z Wu, Y Chen, M Wang, AJ Chung - Lab on a Chip, 2016 - pubs.rsc.org
Fluid inertia which has conventionally been neglected in microfluidics has been gaining
much attention for particle and cell manipulation because inertia-based methods inherently …

Advances in technical assessment of spiral inertial microfluidic devices toward bioparticle separation and profiling: A critical review

M Bagi, F Amjad, SM Ghoreishian… - BioChip Journal, 2024 - Springer
Separation of micro-and nano-sized bioparticles is essential for efficient diagnostics,
chemical and biological analyses, drug development, food and chemical processing, and …

Inertial focusing of spherical particles in rectangular microchannels over a wide range of Reynolds numbers

C Liu, G Hu, X Jiang, J Sun - Lab on a Chip, 2015 - pubs.rsc.org
Inertial microfluidics has emerged as an important tool for manipulating particles and cells.
For a better design of inertial microfluidic devices, we conduct 3D direct numerical …

Inertial separation of particles assisted by symmetrical sheath flows in a straight microchannel

T Zhang, DW Inglis, L Ngo, Y Wang… - Analytical …, 2023 - ACS Publications
Over the past two decades, inertial microfluidics, which works at an intermediate range of
Reynolds number (∼ 1< Re<∼ 100), has been widely used for particle separation due to its …