Inhaled corticosteroids and survival in chronic obstructive pulmonary disease: does the dose matter?

DD Sin, SFP Man - European Respiratory Journal, 2003 - Eur Respiratory Soc
Recent data suggest that inhaled corticosteroids reduce the number of clinical
exacerbations in chronic obstructive pulmonary disease (COPD). It remains unknown …

Inhaled corticosteroids in chronic obstructive pulmonary disease and risk of death and hospitalization: time-dependent analysis

VS Fan, CL Bryson, JR Curtis, SD Fihn… - American journal of …, 2003 - atsjournals.org
Observational studies of inhaled corticosteroids in chronic obstructive pulmonary disease
(COPD) have shown improved survival whereas randomized trials have not. It has been …

Inhaled corticosteroids and mortality in chronic obstructive pulmonary disease

DD Sin, L Wu, JA Anderson, NR Anthonisen, AS Buist… - Thorax, 2005 - thorax.bmj.com
Background: Clinical studies suggest that inhaled corticosteroids reduce exacerbations and
improve health status in chronic obstructive pulmonary disease (COPD). However, their …

Inhaled corticosteroids and the risk of mortality and readmission in elderly patients with chronic obstructive pulmonary disease

DOND SIN, JV TU - American journal of respiratory and critical care …, 2001 - atsjournals.org
There is considerable controversy concerning the utility of inhaled corticosteroids for the
long-term treatment of patients with COPD. Recent studies have suggested that although …

Effectiveness of inhaled corticosteroids in chronic obstructive pulmonary disease: immortal time bias in observational studies

S Suissa - American journal of respiratory and critical care …, 2003 - atsjournals.org
Recent large-scale cohort studies that reported an important reduction in mortality and
chronic obstructive pulmonary disease (COPD) morbidity with inhaled corticosteroids may …

The effects of inhaled corticosteroids in chronic obstructive pulmonary disease: a systematic review of randomized placebo-controlled trials

A Alsaeedi, DD Sin, FA McAlister - The American journal of medicine, 2002 - Elsevier
PURPOSE: Although inhaled corticosteroids are commonly used to treat patients with
chronic obstructive pulmonary disease (COPD), their effect on clinical outcomes such as …

Inhaled corticosteroids and hospitalisation due to exacerbation of COPD

J Bourbeau, P Ernst, D Cockcoft… - European Respiratory …, 2003 - Eur Respiratory Soc
Previous studies have provided conflicting evidence as to the possible benefits of inhaled
corticosteroids in the treatment of chronic obstructive pulmonary disease (COPD). Using the …

Inhaled corticosteroid use in chronic obstructive pulmonary disease and the risk of hospitalization for pneumonia

P Ernst, AV Gonzalez, P Brassard… - American journal of …, 2007 - atsjournals.org
Rationale: Inhaled corticosteroids are commonly prescribed to patients with chronic
obstructive pulmonary disease (COPD). Objectives: To examine whether these medications …

Inhaled corticosteroids in chronic obstructive pulmonary disease: results from two observational designs free of immortal time bias

VA Kiri, NB Pride, JB Soriano… - American journal of …, 2005 - atsjournals.org
Rationale: Recent cohort studies in chronic obstructive pulmonary disease (COPD) have
questioned the validity of previously reported associations between inhaled corticosteroids …

Inhaled corticosteroids and the risk of a first exacerbation in COPD patients

MN De Melo, P Ernst, S Suissa - European Respiratory Journal, 2004 - Eur Respiratory Soc
The role of inhaled corticosteroids (ICS) in asthma is well established, but their benefit in the
management of chronic obstructive pulmonary disease (COPD) is still controversial. The …