microRNA miR-196a-2 and breast cancer: a genetic and epigenetic association study and functional analysis

AE Hoffman, T Zheng, C Yi, D Leaderer, J Weidhaas… - Cancer research, 2009 - AACR
Increasing evidence has suggested that microRNAs (miRNA) play an important role in
tumorigenesis. As transcriptional regulators, altered miRNA expression may affect many …

[HTML][HTML] Differential expression profile and genetic variants of microRNAs sequences in breast cancer patients

AA Alshatwi, G Shafi, TN Hasan, NA Syed… - PloS one, 2012 - journals.plos.org
The technology available for cancer diagnosis and prognosis is not yet satisfactory at the
molecular level, and requires further improvements. Micro RNAs (miRNAs) have been …

A genetic variant in the pre-miR-27a oncogene is associated with a reduced familial breast cancer risk

R Yang, B Schlehe, K Hemminki, C Sutter… - Breast cancer research …, 2010 - Springer
MicroRNAs (miRNAs) regulate pathways involved in cell differentiation, proliferation,
development, and apoptosis by degradation of target mRNAs and/or repression of their …

Novel genetic variants in microRNA genes and familial breast cancer

J Shen, CB Ambrosone, H Zhao - International journal of …, 2009 - Wiley Online Library
MicroRNA (miRNA) plays an important role in tumorigenesis, but whether miRNA is a cancer
predisposition factor or not is still unknown. Considering the fact that miRNA regulates a …

[HTML][HTML] MicroRNAs and their target gene networks in breast cancer

E O'Day, A Lal - Breast cancer research, 2010 - Springer
MicroRNAs (miRNAs) are a major class of small endogenous RNA molecules that post-
transcriptionally inhibit gene expression. Many miRNAs have been implicated in several …

A genetic variant located in miR-423 is associated with reduced breast cancer risk

RA Smith, DJ Jedlinski, PN Gabrovska… - Cancer genomics & …, 2012 - cgp.iiarjournals.org
Background/Aim: Since microRNAs (miRNAs) act as translational regulators of multiple
genes, single nucleotide polymorphisms (SNP) in them can have potentially wide-ranging …

Common genetic variants in pre‐microRNAs were associated with increased risk of breast cancer in Chinese women

Z Hu, J Liang, Z Wang, T Tian, X Zhou, J Chen… - Human …, 2009 - Wiley Online Library
Small, noncoding RNA molecules, called microRNAs (miRNAs), are thought to function as
either tumor suppressors or oncogenes. Common single‐nucleotide polymorphisms (SNPs) …

miR-21-mediated tumor growth

ML Si, S Zhu, H Wu, Z Lu, F Wu, YY Mo - Oncogene, 2007 - nature.com
MicroRNAs (miRNAs) are∼ 22 nucleotide non-coding RNA molecules that regulate gene
expression post-transcriptionally. Although aberrant expression of miRNAs in various …

[HTML][HTML] Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir …

EJH Wee, K Peters, SS Nair, T Hulf, S Stein, S Wagner… - Oncogene, 2012 - nature.com
MicroRNAs (miRNAs) are small non-coding RNAs of∼ 20 nt in length that are capable of
modulating gene expression post-transcriptionally. Although miRNAs have been implicated …

[HTML][HTML] MiR-1287-5p inhibits triple negative breast cancer growth by interaction with phosphoinositide 3-kinase CB, thereby sensitizing cells for PI3Kinase inhibitors

D Schwarzenbacher, C Klec, B Pasculli, S Cerk… - Breast Cancer …, 2019 - Springer
Abstract Background Non-coding RNAs and especially microRNAs have been discovered to
act as master regulators of cancer initiation and progression. The aim of our study was to …