The retinoblastoma (RB) tumor suppressor protein is a transcriptional cofactor with essential
roles in cell cycle and development. Physical and functional targets of RB and its paralogs …

Retinoblastoma proteins are eukaryotic transcriptional corepressors that play central roles in
cell cycle control, among other functions. Although most metazoan genomes encode a …

The retinoblastoma (RB) family transcriptional corepressors regulate diverse cellular events
including cell cycle, senescence, and differentiation. The activity and stability of these …

Retinoblastoma (RB) tumor suppressor proteins are important regulators of the cell cycle
and are implicated in a wide variety of human tumors. Genetic analysis of RB mutations in …

Retinoblastoma tumor suppressor proteins regulate the key transition from G1 to S phase of
the cell cycle. The mammalian Rb family comprises Rb, p107, and p130, with overlapping …

RBf2 is a recently evolved retinoblastoma family member in Drosophila that differs from
RBf1, especially in the C-terminus. To investigate whether the unique features of RBf2 …

The Retinoblastoma (RB) transcriptional corepressor and related family of pocket proteins
play central roles in cell cycle control and development, and the regulatory networks …

Similar to their human counterparts, the Drosophila Rbf1 and Rbf2 Retinoblastoma family
members control cell cycle and developmentally regulated gene expression. Increasing …

Many in vitro and reporter assays have helped to clarify how transcription factors regulate
gene transcription. Today, it is important to decode the map of all transcription factor binding …

The retinoblastoma (RB) family of proteins regulate transcription. These proteins lack
intrinsic DNA-binding activity but are recruited to specific genomic locations through …