Cytogenetic findings and their clinical relevance in myelofibrosis with myeloid metaplasia

A Tefferi, RA Mesa, G Schroeder… - British journal of …, 2001 - Wiley Online Library
The prognostic significance of bone marrow cytogenetic lesions in myelofibrosis with
myeloid metaplasia (MMM) was investigated in a retrospective series of 165 patients. An …

A compendium of cytogenetic abnormalities in myelofibrosis: molecular and phenotypic correlates in 826 patients

E Wassie, C Finke, N Gangat, TL Lasho… - British journal of …, 2015 - Wiley Online Library
Among 826 patients with primary myelofibrosis (PMF) and analysable metaphases on
cytogenetic studies, 352 (42· 6%) had abnormal karyotype, of which 240 (68· 2%) were sole …

Prognostic diversity among cytogenetic abnormalities in myelofibrosis with myeloid metaplasia

A Tefferi, D Dingli, CY Li, GW Dewald - Cancer, 2005 - Wiley Online Library
Abstract BACKGROUND Approximately 30–50% of patients with myelofibrosis with myeloid
metaplasia (MMM) demonstrate detectable cytogenetic abnormalities, the prognostic value …

A prognostic classification of myelofibrosis with myeloid metaplasia

G Barosi, C Berzuini, LN Liberato… - British journal of …, 1988 - Wiley Online Library
The dependence of survival time on a set of prognostic factors was explored by means of
Cox's regression model in 137 cases of myelofibrosis with myeloid metaplasia (MMM). The …

Cytogenetic abnormalities and their prognostic significance in idiopathic myelofibrosis: a study of 106 cases

JT Reilly, JA Snowden, RL Spearing… - British journal of …, 1997 - Wiley Online Library
The prognostic significance of cytogenetic abnormalities was determined in 106 patients
with well‐characterized idiopathic myelofibrosis who were successfully karyotyped at …

Leukemic transformation in myelofibrosis with myeloid metaplasia: a single-institution experience with 91 cases

RA Mesa, CY Li, RP Ketterling, GS Schroeder… - Blood, 2005 - ashpublications.org
Among 2333 consecutive patients with myelofibrosis with myeloid metaplasia (MMM) seen
at our institution, 91 fulfilled the World Health Organization (WHO) criteria for leukemic …

Myelofibrosis with myeloid metaplasia: clinical and haematological parameters predicting survival in a series of 133 patients

G Visani, C Finelli, U Castelli, MC Petti… - British journal of …, 1990 - Wiley Online Library
The prognostic value of 12 clinical and haematological parameters, recorded at diagnosis,
in myelofibrosis with myeloid metaplasia (MMM) was retrospectively analysed in a …

Myelofibrosis with myeloid metaplasia in young indidviduals: disease characteristics, prognostic factors and identification of risk groups

F Cervantes, G Barosi, JL Demory… - British journal of …, 1998 - Wiley Online Library
Myelofibrosis with myeloid metaplasia (MMM) is an uncommon disorder in young
individuals, for whom haemopoietic stem cell transplantation offers the only possibility of …

The role of cytogenetic abnormalities as a prognostic marker in primary myelofibrosis: applicability at the time of diagnosis and later during disease course

CS Tam, LV Abruzzo, KI Lin, J Cortes… - Blood, The Journal …, 2009 - ashpublications.org
Although cytogenetic abnormalities are important prognostic factors in myeloid
malignancies, they are not included in current prognostic scores for primary myelofibrosis …

Refined cytogenetic-risk categorization for overall and leukemia-free survival in primary myelofibrosis: a single center study of 433 patients

D Caramazza, KH Begna, N Gangat, R Vaidya… - Leukemia, 2011 - nature.com
We have previously identified sole+ 9, 13q-or 20q-, as 'favorable'and sole+ 8 or complex
karyotype as 'unfavorable'cytogenetic abnormalities in primary myelofibrosis (PMF). In this …