Indoles as therapeutics of interest in medicinal chemistry: Bird's eye view
N Chadha, O Silakari - European Journal of Medicinal Chemistry, 2017 - Elsevier
Indoles constitute extensively explored heterocyclic ring systems with wide range of
applications in pathophysiological conditions that is, cancer, microbial and viral infections …
applications in pathophysiological conditions that is, cancer, microbial and viral infections …
Medicinal chemistry of indole derivatives: Current to future therapeutic prospectives
A Kumari, RK Singh - Bioorganic chemistry, 2019 - Elsevier
Indole is a versatile pharmacophore, a privileged scaffold and an outstanding heterocyclic
compound with wide ranges of pharmacological activities due to different mechanisms of …
compound with wide ranges of pharmacological activities due to different mechanisms of …
The Multi‐Pharmacological Targeted Role of Indole and its Derivatives: A review
B Suliphuldevara Mathada… - …, 2023 - Wiley Online Library
Heterocycles are a privileged motif that appears as a momentous objective in medicinal
chemistry. An important class of compounds for drug discovery and design is indole and its …
chemistry. An important class of compounds for drug discovery and design is indole and its …
Medicinal perspective of indole derivatives: recent developments and structure-activity relationship studies
Heterocyclic compounds play a significant role in various biological processes of the human
body and many of them are in clinical use due to their diverse, chemical and biological …
body and many of them are in clinical use due to their diverse, chemical and biological …
Recent progress in biological activities of indole and indole alkaloids
The indole scaffold is found in a wide range of bioactive heterocycles and natural products.
Moreover, the indole moiety is considered as the active principle in several alkaloids such …
Moreover, the indole moiety is considered as the active principle in several alkaloids such …
Harnessing the chemistry of the indole heterocycle to drive discoveries in biology and medicine
VM Norwood IV, RW Huigens III - ChemBioChem, 2019 - Wiley Online Library
Indole‐containing compounds demonstrate an array of biological activities relevant to
numerous human diseases. The biological activities of diverse indole‐based agents are …
numerous human diseases. The biological activities of diverse indole‐based agents are …
[HTML][HTML] A brief review of the biological potential of indole derivatives
S Kumar, Ritika - Future Journal of Pharmaceutical Sciences, 2020 - Springer
Background Various bioactive aromatic compounds containing the indole nucleus showed
clinical and biological applications. Indole scaffold has been found in many of the important …
clinical and biological applications. Indole scaffold has been found in many of the important …
[HTML][HTML] Biomedical importance of indoles
The indole nucleus is an important element of many natural and synthetic molecules with
significant biological activity. This review covers some of the relevant and recent …
significant biological activity. This review covers some of the relevant and recent …
An insight into the medicinal perspective of synthetic analogs of indole: A review
PV Thanikachalam, RK Maurya, V Garg… - European journal of …, 2019 - Elsevier
Heterocycles occupy a salient place in chemistry due to their wide range of activity in the
fields of drug design, photochemistry, agrochemicals, dyes, and so on. Amongst all, indole …
fields of drug design, photochemistry, agrochemicals, dyes, and so on. Amongst all, indole …
[HTML][HTML] Synthesis of indole derivatives as prevalent moieties present in selected alkaloids
MM Heravi, Z Amiri, K Kafshdarzadeh, V Zadsirjan - RSC advances, 2021 - pubs.rsc.org
Indoles are a significant heterocyclic system in natural products and drugs. They are
important types of molecules and natural products and play a main role in cell biology. The …
important types of molecules and natural products and play a main role in cell biology. The …
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