Although adhesion to host cells is a critical step in the delivery of cytotoxic Yop proteins by
Yersinia pestis, the mechanism has not been defined. To identify adhesins critical for Yop …

To establish a successful infection, Yersinia pestis requires the delivery of cytotoxic Yops to
host cells. Yops inhibit phagocytosis, block cytokine responses, and induce apoptosis of …

Yersinia pestis, the causative agent of plague, evades host immune responses and rapidly
causes disease. The Y. pestis adhesin Ail mediates host cell binding and is critical for Yop …

Yersinia pestis, the causative agent of plague, exports a set of virulence proteins called
Yops upon contact with eukaryotic cells. A subset of these Yops is translocated directly into …

The goal of this study was to characterize the Yersinia pestis KIM OmpX protein. Yersinia
spp. provide a model for studying several virulence processes including attachment to, and …

Yersinia pestis, the etiologic agent of plague, delivers six Yersinia outer proteins (Yops) into
host cells upon direct bacterial contact. One of these, YopM, is necessary for virulence in a …

Yersinia pestis is one of the most virulent bacteria identified. It is the causative agent of
plague—a systemic disease that has claimed millions of human lives throughout history. Y …

The causative agent of plague, Yersinia pestis, is regarded as being noninvasive for
epithelial cells and lacks the major adhesins and invasins of its enteropathogenic relatives …

Following contact with a eucaryotic cell, Yersinia species pathogenic for humans (Y. pestis,
Y. pseudotuberculosis, and Y. enterocolitica) export and translocate a distinct set of …

The Yersinia pestis adhesin Ail mediates host cell binding and facilitates delivery of cytotoxic
Yop proteins. Ail from Y. pestis and Y. pseudotuberculosis is identical except for one or two …