Retinoblastoma binding protein 6, another p53 monitor
M Ntwasa - Trends in cancer, 2016 - cell.com
The retinoblastoma binding protein 6 (RBBP6), a p53 negative regulator, is essential for
embryonic development. Its loss-of-function phenotype is similar to mouse double minute …
embryonic development. Its loss-of-function phenotype is similar to mouse double minute …
Expression, purification, and characterisation of the p53 binding domain of Retinoblastoma binding protein 6 (RBBP6)
BL Russell, M Ntwasa - Plos one, 2023 - journals.plos.org
RBBP6 is a 250 kDa eukaryotic protein known to be a negative regulator of p53 and
essential for embryonic development. Furthermore, RBBP6 is a critical element in …
essential for embryonic development. Furthermore, RBBP6 is a critical element in …
The Drosophila RetinoblastomaBinding Protein 6 Family Member Has Two Isoformsand Is Potentially Involved in Embryonic Patterning
R Hull, B Oosthuysen, UF Cajee, L Mokgohloa… - International journal of …, 2015 - mdpi.com
The human retinoblastoma binding protein 6 (RBBP6) is implicated in esophageal, lung,
hepatocellular and colon cancers. Furthermore, RBBP6 was identified as a strong marker for …
hepatocellular and colon cancers. Furthermore, RBBP6 was identified as a strong marker for …
[PDF][PDF] The retinoblastoma binding protein 6 is a potential target for therapeutic drugs
M Ntwasa - Biotechnol. Mol. Biol. Rev, 2008 - academia.edu
The retinoblastoma binding protein 6 (RBBP6) proteins (also called P-53 Associated Cell
Testis Derived (PACT)) are highly upregulated in esophageal cancer and enhance the …
Testis Derived (PACT)) are highly upregulated in esophageal cancer and enhance the …
Expression and function of retinoblastoma binding protein 6 (RBBP6) in human lung cancer
LR Motadi, KD Bhoola, Z Dlamini - Immunobiology, 2011 - Elsevier
Retinoblastoma binding protein 6 (RBBP6) interacts with both p53 and pRb, and has been
identified as an E3 ubiquitin ligase due to the presence of a RING finger domain. RBBP6 …
identified as an E3 ubiquitin ligase due to the presence of a RING finger domain. RBBP6 …
Solution structure of RING finger-like domain of retinoblastoma-binding protein-6 (RBBP6) suggests it functions as a U-box
MA Kappo, AB Eiso, F Hassem, RA Atkinson… - Journal of Biological …, 2012 - ASBMB
Retinoblastoma-binding protein-6 (RBBP6) plays a facilitating role, through its RING finger-
like domain, in the ubiquitination of p53 by Hdm2 that is suggestive of E4-like activity …
like domain, in the ubiquitination of p53 by Hdm2 that is suggestive of E4-like activity …
Expression Analysis of RbBP6 in human cancers: a Prospective biomarker
Abstract Retinoblastoma binding protein 6 (RBBP6) is a cancer-related protein that has
been implicated in the regulation of cell cycle and apoptosis. RBBP6 isoform 1 has been …
been implicated in the regulation of cell cycle and apoptosis. RBBP6 isoform 1 has been …
De-regulation of the RBBP6 isoform 3/DWNN in human cancers
Abstract Retinoblastoma binding protein 6 (RBBP6) is a nuclear protein, previously
implicated in the regulation of cell cycle and apoptosis. The human RBBP6 gene codes for …
implicated in the regulation of cell cycle and apoptosis. The human RBBP6 gene codes for …
[HTML][HTML] Retinoblastoma-binding protein 2-homolog 1: a retinoblastoma-binding protein downregulated in malignant melanomas
A Roesch, B Becker, S Meyer, P Wild, C Hafner… - Modern Pathology, 2005 - Elsevier
In malignant melanomas, the loss of cell cycle control is thought to be due to a lack of
retinoblastoma protein (pRb)-activity. Members of the previously described family of …
retinoblastoma protein (pRb)-activity. Members of the previously described family of …
[PDF][PDF] Implications of RBBP6 in various types of cancer.
Background: The 2 50 k Da r etinoblastoma bi nding pr otein 6 (RBBP6) was cloned over a
decade ago and was found to bind both the p53 and Rb1 tumor suppressor proteins. In …
decade ago and was found to bind both the p53 and Rb1 tumor suppressor proteins. In …