Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies
J Gao, Z Tian, X Yang - Bioscience trends, 2020 - jstage.jst.go.jp
Abstract The coronavirus disease 2019 (COVID-19) virus is spreading rapidly, and scientists
are endeavoring to discover drugs for its efficacious treatment in China. Chloroquine …
are endeavoring to discover drugs for its efficacious treatment in China. Chloroquine …
[HTML][HTML] Drug repurposing in COVID-19: a review with past, present and future
K Srivastava, MK Singh - Metabolism Open, 2021 - Elsevier
The coronavirus SARS-CoV-2 which causes the COVID-19 disease is a global public health
emergency. Coronavirus are single-stranded positive-sense RNA viruses and their genome …
emergency. Coronavirus are single-stranded positive-sense RNA viruses and their genome …
[HTML][HTML] Clinical efficacy of chloroquine derivatives in COVID-19 infection: comparative meta-analysis between the big data and the real world
In the context of the current coronavirus disease 2019 (COVID-19) pandemic, we conducted
a meta-analysis on the effects of chloroquine derivatives in patients, based on unpublished …
a meta-analysis on the effects of chloroquine derivatives in patients, based on unpublished …
Hydroxychloroquine as an aerosol might markedly reduce and even prevent severe clinical symptoms after SARS-CoV-2 infection
A Klimke, G Hefner, B Will, U Voss - Medical hypotheses, 2020 - Elsevier
Covid-19 is a new coronavirus disease first described in December 2019. This respiratory
illness is severe and potentially fatal. Severe cases make up to 15%, lethality ranges …
illness is severe and potentially fatal. Severe cases make up to 15%, lethality ranges …
Pharmacokinetics and pharmacological properties of chloroquine and hydroxychloroquine in the context of COVID‐19 infection
Chloroquine and hydroxychloroquine are quinoline derivatives used to treat malaria. To
date, these medications are not approved for the treatment of viral infections, and there are …
date, these medications are not approved for the treatment of viral infections, and there are …
Chloroquine as a potential treatment and prevention measure for the 2019 novel coronavirus: a review
J Kearney - 2020 - preprints.org
There is a long trail of research studies testing the in vitro and in vivo efficacy of chloroquine
and its derivatives in treating and preventing infection by various coronavirus species. More …
and its derivatives in treating and preventing infection by various coronavirus species. More …
Colchicine treatment can improve outcomes of coronavirus disease 2019 (COVID‐19): a systematic review and meta‐analysis
TI Hariyanto, DA Halim, C Jodhinata… - Clinical and …, 2021 - Wiley Online Library
Currently, there is no widely acceptable and proven effective treatment for coronavirus
disease 2019 (COVID‐19). Colchicine has been shown to offer a benefit in reducing the …
disease 2019 (COVID‐19). Colchicine has been shown to offer a benefit in reducing the …
Clozapine treatment and risk of COVID-19 infection: retrospective cohort study
R Govind, DF de Freitas, M Pritchard… - The British journal of …, 2021 - cambridge.org
BackgroundClozapine, an antipsychotic with unique efficacy in treatment-resistant
psychosis, is associated with increased susceptibility to infection, including pneumonia …
psychosis, is associated with increased susceptibility to infection, including pneumonia …
Sequential doxycycline and colchicine combination therapy in Covid-19: the salutary effects
Abstract Coronavirus virus disease 2019 (COVID-19) is a viral infectious disease caused by
the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), actually considered as …
the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), actually considered as …
Chloroquine and hydroxychloroquine for COVID‐19: Perspectives on their failure in repurposing
RR Shah - Journal of clinical pharmacy and therapeutics, 2021 - Wiley Online Library
What is known and Objective Non‐clinical studies suggest that chloroquine (CQ) and
hydroxychloroquine (HCQ) have antiviral activities. Early clinical reports of successful HCQ …
hydroxychloroquine (HCQ) have antiviral activities. Early clinical reports of successful HCQ …