[HTML][HTML] MEG3 promotes proliferation and inhibits apoptosis in osteoarthritis chondrocytes by miR-361-5p/FOXO1 axis
A Wang, N Hu, Y Zhang, Y Chen, C Su, Y Lv… - BMC Medical …, 2019 - Springer
Background This study aimed to investigate the role of long non-coding RNA (lncRNA)
maternally expressed 3 (MEG3) and related molecular mechanisms, in osteoarthritis (OA) …
maternally expressed 3 (MEG3) and related molecular mechanisms, in osteoarthritis (OA) …
[HTML][HTML] LncRNA MEG3 Protects Chondrocytes From IL-1β-Induced Inflammation via Regulating miR-9-5p/KLF4 Axis
Y Huang, D Chen, Z Yan, J Zhan, X Xue, X Pan… - Frontiers in …, 2021 - frontiersin.org
Background Osteoarthritis (OA) is a chronic degenerative disease of the joints characterized
by articular cartilage damage, subchondral bone remodeling, osteophyte formation, and …
by articular cartilage damage, subchondral bone remodeling, osteophyte formation, and …
[HTML][HTML] lncRNA MEG8 is downregulated in osteoarthritis and regulates chondrocyte cell proliferation, apoptosis and inflammation
W Xie, L Jiang, X Huang, H Shang… - Experimental and …, 2021 - spandidos-publications.com
Long noncoding RNA (lncRNA) maternally expressed 8, small nucleolar RNA host gene
(MEG8) has been widely reported for its pro‑proliferative, anti‑apoptotic and anti …
(MEG8) has been widely reported for its pro‑proliferative, anti‑apoptotic and anti …
[HTML][HTML] The lncRNA MEG3 downregulation leads to osteoarthritis progression via miR-16/SMAD7 axis
J Xu, Y Xu - Cell & bioscience, 2017 - Springer
Background Osteoarthritis (OA) is a chronic joint disease and there is no a definitive cure at
present. Long non-coding RNAs (lncRNAs) have been confirmed to play important roles in …
present. Long non-coding RNAs (lncRNAs) have been confirmed to play important roles in …
miR-7/EGFR/MEGF9 axis regulates cartilage degradation in osteoarthritis via PI3K/AKT/mTOR signaling pathway
L Jiang, X Zhou, K Xu, P Hu, J Bao, J Li, J Zhu… - …, 2021 - Taylor & Francis
Osteoarthritis (OA) is a common degenerative disease in middle-aged and elderly people.
Our previous study has proved that microRNA-7 (miR-7) exacerbated the OA process. This …
Our previous study has proved that microRNA-7 (miR-7) exacerbated the OA process. This …
The long noncoding RNA MEG3 is downregulated and inversely associated with VEGF levels in osteoarthritis
W Su, W Xie, Q Shang, B Su - BioMed research international, 2015 - Wiley Online Library
Osteoarthritis (OA) is becoming a major public health problem in China, especially
considering the increase in average life expectancy of the population. Thus, enhanced …
considering the increase in average life expectancy of the population. Thus, enhanced …
LncRNA MEG3 inhibits the degradation of the extracellular matrix of chondrocytes in osteoarthritis via targeting miR-93/TGFBR2 axis
K Chen, H Zhu, MQ Zheng, QR Dong - Cartilage, 2021 - journals.sagepub.com
Background As a degenerative joint disease, osteoarthritis (OA) is characterized by articular
cartilage degradation. Long noncoding RNAs (lncRNAs) act critical roles in the regulation of …
cartilage degradation. Long noncoding RNAs (lncRNAs) act critical roles in the regulation of …
MiR-337-3p promotes chondrocytes proliferation and inhibits apoptosis by regulating PTEN/AKT axis in osteoarthritis
Z Huang, N Zhang, W Ma, X Dai, J Liu - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Background Osteoarthritis (OA) is a degenerative disease of articular cartilage and its main
pathological feature is cartilage destruction, but its specific pathogenesis is still debatable …
pathological feature is cartilage destruction, but its specific pathogenesis is still debatable …
MIR-140-5p affects chondrocyte proliferation, apoptosis, and inflammation by targeting HMGB1 in osteoarthritis
Y Wang, S Shen, Z Li, W Li, X Weng - Inflammation Research, 2020 - Springer
Objective This study aimed to test the expression and biological function of miR-140-5p in
osteoarthritis (OA), and identify its target gene and explore its mechanism in OA. Methods …
osteoarthritis (OA), and identify its target gene and explore its mechanism in OA. Methods …
[HTML][HTML] miR‑17‑5p and miR‑19b‑3p prevent osteoarthritis progression by targeting EZH2
Y Li, F Yuan, Y Song, X Guan - Experimental and …, 2020 - spandidos-publications.com
Osteoarthritis (OA) is a joint disease caused by a variety of factors, including aging, obesity
and trauma. MicroRNAs (miRNAs) have been reported to be crucial regulators during OA …
and trauma. MicroRNAs (miRNAs) have been reported to be crucial regulators during OA …