High Level of var2csa Transcription by Plasmodium falciparum Isolated from the Placenta
NG Tuikue Ndam, A Salanti, G Bertin… - The Journal of …, 2005 - academic.oup.com
Plasmodium falciparum parasites that bind to chondroitin sulphate A (CSA) express unique
variant surface antigens that are involved in the placental sequestration that precipitates …
variant surface antigens that are involved in the placental sequestration that precipitates …
The antibody response of pregnant Cameroonian women to VAR2CSA ID1-ID2a, a small recombinant protein containing the CSA-binding site
A Babakhanyan, RGF Leke, A Salanti, N Bobbili… - PloS one, 2014 - journals.plos.org
In pregnant women, Plasmodium falciparum-infected erythrocytes expressing the VAR2CSA
antigen bind to chondroitin sulfate A in the placenta causing placental malaria. The binding …
antigen bind to chondroitin sulfate A in the placenta causing placental malaria. The binding …
A single full-length VAR2CSA ectodomain variant purifies broadly neutralizing antibodies against placental malaria isolates
JYA Doritchamou, JP Renn, B Jenkins, A Mahamar… - Elife, 2022 - elifesciences.org
Placental malaria (PM) is a deadly syndrome most frequent and severe in first pregnancies.
PM results from accumulation of Plasmodium falciparum-infected erythrocytes (IE) that …
PM results from accumulation of Plasmodium falciparum-infected erythrocytes (IE) that …
Characterization of VAR2CSA-deficient Plasmodium falciparum-infected erythrocytes selected for adhesion to the BeWo placental cell line
F Yosaatmadja, KT Andrews, MF Duffy, GV Brown… - Malaria journal, 2008 - Springer
Background Malaria in pregnancy is characterized by accumulation of infected erythrocytes
(IE) in the placenta. The key ligand identified as mediating this process is a Plasmodium …
(IE) in the placenta. The key ligand identified as mediating this process is a Plasmodium …
Differential Induction of Functional IgG Using the Plasmodium falciparum Placental Malaria Vaccine Candidate VAR2CSA
VV Pinto, SB Ditlev, KE Jensen, M Resende… - PloS one, 2011 - journals.plos.org
Background In Plasmodium falciparum malaria endemic areas placental malaria (PM) is an
important complication of malaria. The recurrence of malaria in primigravidae women …
important complication of malaria. The recurrence of malaria in primigravidae women …
Antigenic Differences and Conservation among Placental Plasmodium falciparum–Infected Erythrocytes and Acquisition of Variant-Specific and Cross-Reactive …
JG Beeson, EJ Mann, TJ Byrne… - The Journal of …, 2006 - academic.oup.com
Background Pregnant women are infected by Plasmodium falciparum with novel antigenic
phenotypes that adhere to chondroitin sulfate A (CSA) and other receptors in the placenta …
phenotypes that adhere to chondroitin sulfate A (CSA) and other receptors in the placenta …
Recovery of adhesion to chondroitin‐4‐sulphate in Plasmodium falciparum var CSA disruption mutants by antigenically similar PfEMP1 variants
KT Andrews, LA Pirrit, JM Przyborski… - Molecular …, 2003 - Wiley Online Library
Protection against maternal malaria has been associated with the acquisition of a specific
antibody response that prevents adhesion of Plasmodium falciparum‐infected erythrocytes …
antibody response that prevents adhesion of Plasmodium falciparum‐infected erythrocytes …
Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein
Plasmodium vivax Duffy Binding Protein (PvDBP) is the most promising vaccine candidate
for P. vivax malaria. The polymorphic nature of PvDBP induces strain-specific immune …
for P. vivax malaria. The polymorphic nature of PvDBP induces strain-specific immune …
Identification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSA
M Resende, MA Nielsen, M Dahlbäck, SB Ditlev… - Malaria Journal, 2008 - Springer
Background Pregnancy malaria is caused by Plasmodium falciparum-infected erythrocytes
binding the placental receptor chondroitin sulfate A (CSA). This results in accumulation of …
binding the placental receptor chondroitin sulfate A (CSA). This results in accumulation of …
Functional and Immunological Characterization of a Duffy Binding–Like–γ Domain from Plasmodium falciparum Erythrocyte Membrane Protein–1 Expressed by a …
YS Chia, C Badaut, NG Tuikue Ndam… - The Journal of …, 2005 - academic.oup.com
A recombinant Duffy binding–like (DBL)–γ domain from a previously identified placental
isolate, 732, was expressed by use of the baculovirus/insect cell system and was purified in …
isolate, 732, was expressed by use of the baculovirus/insect cell system and was purified in …