Molecular markers for novel therapeutic strategies in pancreatic endocrine tumors

JA Gilbert, LJ Adhikari, RV Lloyd, TR Halfdanarson… - Pancreas, 2013 - journals.lww.com
Objectives Pancreatic endocrine tumors (PETs) share numerous features with
gastrointestinal neuroendocrine (carcinoid) tumors. Targets of novel therapeutic strategies …

[HTML][HTML] Pancreatic endocrine tumours: mutational and immunohistochemical survey of protein kinases reveals alterations in targetable kinases in cancer cell lines …

V Corbo, S Beghelli, S Bersani, D Antonello… - Annals of …, 2012 - Elsevier
Background Kinases represent potential therapeutic targets in pancreatic endocrine tumours
(PETs). Patients and methods Thirty-five kinase genes were sequenced in 36 primary PETs …

Gastroenteropancreatic neuroendocrine tumors: update on therapeutics

A Ganetsky, V Bhatt - Annals of Pharmacotherapy, 2012 - journals.sagepub.com
OBJECTIVE: To review the available literature addressing the treatment of pancreatic
neuroendocrine tumors (PNETs) and carcinoid tumors. DATA SOURCES: Relevant literature …

[PDF][PDF] Molecular markers for novel therapies in neuroendocrine (carcinoid) tumors

JA Gilbert, LJ Adhikari, RV Lloyd, J Rubin… - Endocrine-related …, 2010 - academia.edu
Abstract Neuroendocrine (carcinoid) tumors (NETs) are endocrine neoplasms occurring
most frequently in gastrointestinal and bronchopulmonary (BP) systems. The majority of …

[HTML][HTML] Pancreatic endocrine tumors: expression profiling evidences a role for AKT-mTOR pathway

E Missiaglia, I Dalai, S Barbi, S Beghelli… - Journal of clinical …, 2010 - ncbi.nlm.nih.gov
Pancreatic Endocrine Tumors: Expression Profiling Evidences a Role for AKT-mTOR Pathway
- PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …

Pancreatic neuroendocrine and carcinoid tumors: what's new, what's old, and what's different?

D Reidy-Lagunes, R Thornton - Current oncology reports, 2012 - Springer
Well-differentiated neuroendocrine tumors (NETs) can be subdivided into carcinoid and
pancreatic NETs (panNETs). Recently, two therapies have been FDA approved for …

Pancreatic neuroendocrine tumors: molecular mechanisms and therapeutic targets

CK Maharjan, PH Ear, CG Tran, JR Howe… - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic neuroendocrine tumors (pNETs) are rare, indolent cancers
whose causation is only partly understood. An increasing number of studies have uncovered …

[HTML][HTML] Molecular pathology of pancreatic neuroendocrine tumors

M Chen, M Van Ness, Y Guo… - Journal of gastrointestinal …, 2012 - ncbi.nlm.nih.gov
Pancreatic endocrine tumors (PETs) are rare neoplasms which account for 1% to 2% of all
pancreatic malignancies. The diagnostic, grading and prognostic criteria for PETs have …

Defining molecular classifications and targets in gastroenteropancreatic neuroendocrine tumors through DNA microarray analysis

EM Duerr, Y Mizukami, A Ng, RJ Xavier… - Endocrine-related …, 2008 - erc.bioscientifica.com
Current classifications of human gastroenteropancreatic neuroendocrine tumors (NETs) are
inconsistent and based upon histopathologic but not molecular features. We sought to …

Molecular profile of pancreatic neuroendocrine neoplasms (PanNENs): Opportunities for personalized therapies

J Arakelyan, D Zohrabyan, PA Philip - Cancer, 2021 - Wiley Online Library
Pancreatic neuroendocrine neoplasms (panNENs) are the second most common epithelial
tumors of the pancreas. Despite improvements in prognostic grading and staging systems, it …