Serial quantification of residual disease in CML patients after allogeneic BMT is useful for
early detection of relapse. However, the fact that some cytogenetic relapses appear to be …

The monitoring of minimal residual disease (MRD) through low sensitivity real-time (RT)
polymerase chain reaction (PCR) analysis of BCR-ABL transcripts allows early detection of …

Real‐time quantitative reverse transcription‐polymerase chain reaction (Q‐RT‐PCR) is
increasingly used to monitor responses in chronic myeloid leukaemia (CML). The peripheral …

Recent progress in the development of diagnostic techniques has greatly facilitated the
monitoring of minimal residual disease (MRD) in patients with hematologic neoplasia. The …

The polymerase chain reaction (PCR) allows the detection of minimal amounts of nucleic
sequences and has been successfully used to test for the chronic myeloid leukemia-specific …

Real-time quantitative polymerase chain reaction (PCR) for BCR-ABL mRNA in the
peripheral blood (RQ-PCR) provides an accurate and reliable measure of response to …

1Department of Hematology-Oncology" L. and A. Seràgnoli" University of Bologna, Bologna;
2Onco-Hematology Unit, University of Naples Federico II and CEINGE, Biotecnologie …

We have sought to determine whether peripheral blood or bone marrow is more sensitive for
assessment of minimal residual disease in chronic myeloid leukaemia (CML) …

BACKGROUND AND OBJECTIVES: Imatinib is the new standard drug treatment for patients
with chronic myelogenous leukemia (CML). Quantitative reverse transcription-polymerase …

In order to analyze the efficiency of interphase FISH for the detection and monitoring of Ph+
cells in chronic myelogenous leukemia (CML) under interferon (IFN) treatment, the following …