Spinal cord injury (SCI) is characterized by an initial trauma followed by a progressive
cascade of damage referred to as secondary injury. A hallmark of secondary injury is …

The mitochondrion is a double membrane structured organelle involved in a variety of
regulatory functions such as calcium signaling, production of adenosine triphosphate …

Traumatic injury to the mammalian spinal cord is a highly dynamic process characterized by
a complex pattern of pervasive and destructive biochemical and pathophysiological events …

Many people around the world suffer from some form of paralysis caused by spinal cord
injury (SCI), which has an impact on quality and life expectancy. The spinal cord is part of …

Despite numerous studies reporting some measures of efficacy in the animal literature, there
are currently no effective therapies for the treatment of traumatic spinal cord injuries (SCI) in …

Mitochondria are dynamic organelles responsible for cellular energy production. Besides,
regulating energy homeostasis, mitochondria are responsible for calcium homeostasis …

Traumatic brain injury (TBI) is one of the most prevalent causes of permanent physical and
cognitive disabilities. TBI pathology results from primary insults and a multi‐mechanistic …

Mitochondrial dysfunction following spinal cord injury (SCI) may be critical for the
development of secondary pathophysiology and neuronal cell death. Previous studies have …

Traumatic brain injury (TBI) is still the leading cause of disability in young adults worldwide.
The major mechanisms–diffuse axonal injury, cerebral contusion, ischemic neurological …

Traumatic brain injury is a complicated disease to treat due to the complex multi-factorial
secondary injury cascade that is initiated following the initial impact. This secondary injury …