Andrographolide acts as an anti-inflammatory agent in LPS-stimulated RAW264. 7 macrophages by inhibiting STAT3-mediated suppression of the NF-κB pathway
KC Lee, HH Chang, YH Chung, TY Lee - Journal of ethnopharmacology, 2011 - Elsevier
Ethnopharmacological significance Inflammation is involved in numerous diseases, such as
chronic inflammatory disease and cancer. Many plant products exhibit useful biological …
chronic inflammatory disease and cancer. Many plant products exhibit useful biological …
Andrographolide Inhibits Inflammatory Cytokines Secretion in LPS‐Stimulated RAW264.7 Cells through Suppression of NF‐κB/MAPK Signaling Pathway
Y Li, S He, J Tang, N Ding, X Chu… - Evidence‐Based …, 2017 - Wiley Online Library
Andrographolide, the main active component extracted from Andrographis paniculata (Burm.
f.) Wall. ex Nees, exerts anti‐inflammatory effects; however, the principal molecular …
f.) Wall. ex Nees, exerts anti‐inflammatory effects; however, the principal molecular …
Inhibitory effects of andrographolide on activated macrophages and adjuvant-induced arthritis
Andrographolide, a diterpenoid lactone obtained from plant Andrographis paniculata, is
used in South Asian countries to relieve various inflammatory symptoms. To study the effects …
used in South Asian countries to relieve various inflammatory symptoms. To study the effects …
[HTML][HTML] Andrographolide inhibits inflammatory responses in LPS-stimulated macrophages and murine acute colitis through activating AMPK
N Kim, P Lertnimitphun, Y Jiang, H Tan, H Zhou… - Biochemical …, 2019 - Elsevier
Abstract Andrographolide (Andro), a well-known labdane diterpenoid of Andrographis
paniculata, has been reported to have anti-inflammatory effects in various inflammatory …
paniculata, has been reported to have anti-inflammatory effects in various inflammatory …
Inhibition of TNF-α-Induced Inflammation by andrographolide via down-regulation of the PI3K/Akt signaling pathway
HW Chen, AH Lin, HC Chu, CC Li… - Journal of natural …, 2011 - ACS Publications
Andrographolide (1), an active constituent of Andrographis paniculata, decreased tumor
necrosis factor-α (TNF-α)-induced intercellular adhesion molecule-1 (ICAM-1) expression …
necrosis factor-α (TNF-α)-induced intercellular adhesion molecule-1 (ICAM-1) expression …
Andrographolide antagonizes TNF-α-induced IL-8 via inhibition of NADPH oxidase/ROS/NF-κB and Src/MAPKs/AP-1 axis in human colorectal cancer HCT116 cells
M Yuan, W Meng, W Liao, S Lian - Journal of agricultural and food …, 2018 - ACS Publications
Andrographis paniculata Nees is used as a functional food in Japan, Korea, India, and
China. Andrographolide, a naturally occurring phytochemical identified in Andrographis …
China. Andrographolide, a naturally occurring phytochemical identified in Andrographis …
AP‐1/IRF‐3 Targeted Anti‐Inflammatory Activity of Andrographolide Isolated from Andrographis paniculata
Andrographolide (AG) is an abundant component of plants of the genus Andrographis and
has a number of beneficial properties including neuroprotective, anticancer, anti …
has a number of beneficial properties including neuroprotective, anticancer, anti …
[HTML][HTML] Andrographolide, a natural anti-inflammatory agent: An Update
X Li, W Yuan, J Wu, J Zhen, Q Sun, M Yu - Frontiers in pharmacology, 2022 - frontiersin.org
Botanicals have attracted much attention in the field of anti-inflammatory due to their good
pharmacological activity and efficacy. Andrographis paniculata is a natural plant ingredient …
pharmacological activity and efficacy. Andrographis paniculata is a natural plant ingredient …
Andrographolide attenuates inflammation by inhibition of NF-κB activation through covalent modification of reduced cysteine 62 of p50
YF Xia, BQ Ye, YD Li, JG Wang, XJ He… - The Journal of …, 2004 - journals.aai.org
NF-κB is a central transcriptional factor and a pleiotropic regulator of many genes involved in
immunological responses. During the screening of a plant extract library of traditional …
immunological responses. During the screening of a plant extract library of traditional …
Is there a future for andrographolide to be an anti-inflammatory drug? Deciphering its major mechanisms of action
Andrographis paniculata has long been part of the traditional herbal medicine system in
Asia and in Scandinavia. Andrographolide was isolated as a major bioactive constituent of …
Asia and in Scandinavia. Andrographolide was isolated as a major bioactive constituent of …