The role of cholesterol in membrane fusion

ST Yang, AJB Kreutzberger, J Lee, V Kiessling… - Chemistry and physics …, 2016 - Elsevier
Cholesterol modulates the bilayer structure of biological membranes in multiple ways. It
changes the fluidity, thickness, compressibility, water penetration and intrinsic curvature of …

Modulation of entry of enveloped viruses by cholesterol and sphingolipids

SS Rawat, M Viard, SA Gallo, A Rein… - Molecular membrane …, 2003 - Taylor & Francis
Enveloped animal viruses infect host cells by fusion of viral and target membranes. This
crucial fusion event occurs either with the plasma membrane of the host cells at the …

[HTML][HTML] Rapid membrane fusion of individual virus particles with supported lipid bilayers

L Wessels, MW Elting, D Scimeca, K Weninger - Biophysical journal, 2007 - cell.com
Many enveloped viruses employ low-pH-triggered membrane fusion during cell penetration.
Solution-based in vitro assays in which viruses fuse with liposomes have provided much of …

Membrane fusion: a structural perspective on the interplay of lipids and proteins

LK Tamm, J Crane, V Kiessling - Current opinion in structural biology, 2003 - Elsevier
The fusion of biological membranes is governed by the carefully orchestrated interplay of
membrane proteins and lipids. Recently determined structures of fusion proteins, individual …

[HTML][HTML] Cholesterol stiffening of lipid membranes

FT Doole, T Kumarage, R Ashkar, MF Brown - The Journal of Membrane …, 2022 - Springer
Biomembrane order, dynamics, and other essential physicochemical parameters are
controlled by cholesterol, a major component of mammalian cell membranes. Although …

[HTML][HTML] Lipids as modulators of membrane fusion mediated by viral fusion proteins

É Teissier, EI Pécheur - European Biophysics Journal, 2007 - Springer
Enveloped viruses infect host cells by fusion of viral and target membranes. This fusion
event is triggered by specific glycoproteins in the viral envelope. Fusion glycoproteins …

Cholesterol's interfacial interactions with sphingomyelins and-phosphatidylcholines: hydrocarbon chain structure determines the magnitude of condensation

JM Smaby, HL Brockman, RE Brown - Biochemistry, 1994 - ACS Publications
Revised Manuscript Received May 18, 1994· abstract: Cholesterol's interfacial interaction
with different sphingomyelins and phosphatidylcholines has been investigated using a …

[HTML][HTML] Sphingolipid and cholesterol dependence of alphavirus membrane fusion: lack of correlation with lipid raft formation in target liposomes

BL Waarts, R Bittman, J Wilschut - Journal of Biological Chemistry, 2002 - ASBMB
Semliki Forest virus (SFV) and Sindbis virus (SIN) are enveloped viruses that infect their host
cells by receptor-mediated endocytosis and subsequent fusion from within acidic …

Membrane fusion: lipid vesicles as a model system

J Wilschut, D Hoekstra - Chemistry and physics of lipids, 1986 - Elsevier
In many cellular functions the process of membrane fusion is of vital importance. It occurs in
a highly specific and strictly controlled fashion. Proteins are likely to play a key role in the …

[HTML][HTML] Mechanism of membrane fusion: interplay of lipid and peptide

A Joardar, GP Pattnaik, H Chakraborty - The Journal of Membrane Biology, 2022 - Springer
Membrane fusion is an essential process for the survival of eukaryotes and the entry of
enveloped viruses into host cells. A proper understanding of the mechanism of membrane …