Design, synthesis, and antifungal activity of nicotinamide derivatives containing diphenylamine moieties

Z Yan, S Liu, L Qiu, Y Chen, A Li, Z Wang… - Journal of Chemical …, 2022 - Springer
In order to find amide compounds with desired antifungal activity, 16 nicotinamide
derivatives containing diphenylamine moieties were prepared by condensation of 2 …

Design, synthesis and antifungal/insecticidal evaluation of novel nicotinamide derivatives

F Wen, H Zhang, Z Yu, H Jin, Q Yang, T Hou - Pesticide biochemistry and …, 2010 - Elsevier
A series of nicotinamide derivatives based on Boscalid were prepared and tested for their
activities against seven plant pathogenic fungi and two insects. The preliminary bioassays …

Design, synthesis and structure-activity relationship studies of nicotinamide derivatives as potent antifungal agents by disrupting cell wall

T Ni, F Xie, L Li, Y Hao, X Chi, L Yan, D Zhang, Y Jiang… - Molecules, 2023 - mdpi.com
Fungal infections pose a serious challenge to human health due to the limited paucity of
antifungal treatments. Starting as a hit compound screened from our compound library, a …

Novel N‐(1H‐Pyrazol‐5‐yl)nicotinamide Derivatives: Design, Synthesis and Antifungal Activity

W Wang, XJ Liu, GT Lin, JP Wu, G Xu… - Chemistry & …, 2022 - Wiley Online Library
To discover more effective antifungal agents, twenty N‐(1H‐pyrazol‐5‐yl) nicotinamide
derivatives were designed, synthesized, and structurally confirmed by 1H‐NMR, 13C‐NMR …

Synthesis, crystal structure, fungicidal activity, molecular docking, and density functional theory study of 2-chloro-N-(p-tolylcarbamoyl) nicotinamide

WT Chen, Q Wang, LJ Min, HK Wu, JQ Weng… - Indian J. Heterocycl …, 2019 - hero.epa.gov
A new nicotine acylurea, 2-chloro-N-(p-tolylcarbamoyl) nicotinamide (4) was synthesized
and its structure was confirmed by proton nuclear magnetic resonance, high resolution mass …

Novel amide derivatives containing a pyridine moiety: design, synthesis as potential fungicides

X Luo, Y Chen, Y Wang, Z Xing, J Peng, C Yi, J Chen - Chemical Papers, 2023 - Springer
To discover new fungicides, a series of amides derivatives containing a pyridine moiety
were designed and synthesized by grafting the pyridine of fluopyram into the boscalid …

Synthesis and antifungal activities of novel nicotinamide derivatives containing 1, 3, 4-oxadiazole

J Wu, S Kang, L Luo, Q Shi, J Ma, J Yin, B Song… - Chemistry Central …, 2013 - Springer
Background Pant diseases in agriculture are extremely difficult to control, which bring about
for billions of dollars in economic losses worldwide each year; Nicotinamide derivatives has …

N‐Nitrourea Derivatives as Novel Potential Fungicides against Rhizoctonia solani: Synthesis, Antifungal Activities, and 3D‐QSAR

X Cao, S Xu, X Li, X Shen, Q Zhang… - Chemical Biology & …, 2012 - Wiley Online Library
A series of N‐nitrourea derivatives bearing various aryl substituents were conveniently
obtained via three steps including nitration, carbamic chlorination, and aminolysis reactions …

Research on crystal structure and fungicidal activity of the amide derivatives based on the natural products sinapic acid and mycophenolic acid

Z Chen, H Fang, X Hua, W Liu, Y Liu, C Xue… - Journal of …, 2021 - Wiley Online Library
Structural optimization based on natural products is an important and effective way to
discover new green pesticides. Here, two series of amide derivatives based on sinapic acid …

Synthesis, cyrstal structure, fungicidal activity and molecular docking of nicotinic acyl urea derivatives

PP Zhang, Q Wang, LJ Min, HK Wu, JQ Weng… - Journal of Molecular …, 2020 - Elsevier
A series of nicotinic acyl urea derivatives were designed using boscalid as a lead
compound. They were synthesized via four steps. Their structures were confirmed by 1 H …