Platelet activation during thrombotic events is closely associated with complement and
contact system activation, which in turn leads to inflammation. Here we review the …

Background Exposure of chondroitin sulfate A (CS-A) on the surface of activated platelets is
well established. The aim of the present study was to investigate to what extent CS-A …

Platelets play an essential role in maintaining homeostasis in the circulatory system after an
injury by forming a platelet thrombus, but they also occupy a central node in the …

Background: Chondroitin sulfate (CS) is a glycosaminoglycan released by activated
platelets. Objective: Here we test the hypothesis that CS released by activated platelets can …

Platelets participate in a variety of responses of the blood to injury. An emerging body of
evidence suggests that these cells express an intrinsic capacity to interact with and trigger …

Inflammation and thrombosis are two responses that are linked through a number of
mechanisms, one of them being the complement system. Various proteins of the …

Objective: Activation of the complement system plays a key role in inflammation associated
with vascular injury. Recently, platelet P‐selectin was shown to activate C3 via the …

The complement system comprises a series of proteases and inhibitors that are activated in
cascade-like fashion during host defense (Makrides 1998). A growing body of evidence …

The complement system is a versatile part of our immune system. Various intersection points
of complement with other cells and molecules of the immune response are well described …

In recent years, the view of platelets has changed from mere elements of hemostasis to
immunological multitaskers. They are connected in manifold ways to other cellular and …