Genome editing technologies have not only enabled the precise targeting of a particular
area of the genome but also eliminated the variability in expression and gene silencing …

Sheep and goats are valuable livestock species that have been raised for their production of
meat, milk, fiber, and other by-products. Due to their suitable size, short gestation period …

The human genome is complex, and the functions of many genes and specific genomic
elements have not been fully explored. Cultured human cells, from conventional cell lines to …

Genome modification technologies are powerful tools for molecular biology and related
areas. Advances in animal transgenesis and genome editing technologies during the past …

The CRISPR/Cas9 system has been applied in a large number of animal and plant species
for genome editing. In chickens, CRISPR has been used to knockout genes in somatic …

We have expanded the livestock gene editing toolbox to include transcription activator-like
(TAL) effector nuclease (TALEN)-and clustered regularly interspaced short palindromic …

The generation of genetically modified animals is important for both research and
commercial purposes. The rat is an important model organism that until recently lacked …

Molecular scissors including zinc finger nucleases, transcription activator-like
endonucleases, and clustered regularly interspaced short palindromic repeats/CRISPR …

Due to its close resemblance, the domesticated pig has proven to be a diverse animal model
for biomedical research and genome editing tools have contributed to developing porcine …

The CRISPR/Cas9 system is widely used for genome editing in livestock production,
although off-target effects can occur. It is the main method to produce genome-edited goats …